Incidence of nausea and vomiting with cytotoxic chemotherapy: a prospective randomised trial of antiemetics.
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Antineoplastic Agents↗
Biomedical subjects
C Morran
Publications and source records attributed to C Morran.
Prophylactic co-trimoxazole in biliary surgery.
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Cholecystectomy↗
Prophylactic co-trimoxazole in biliary surgery.
A double-blind study was conducted to test the prophylactic effect of a single dose of co-trimoxazole on the incidence of septic complications after elective cholecystectomy. Forty-eight patients received co-trimoxazole and 47 placebo. Wound sepsis occurred in 10 (21%) of the controls but in only 2 (4%) of the treated group, and the incidences of pulmonary complications were 49% (23 cases) and 19% (9) respectively. These differences were significnat. Wound sepsis after cholecystectomy occurs mostly in patients with infected bile. Co-trimoxazole given by intravenous infusion rapidly achieves a high concentration in the palsma and is effective against most biliary pathogens.
Cholecystectomy↗