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Biomedical subjects

C Moutsouris

Publications and source records attributed to C Moutsouris.

8 recordsLinked to original sources
PubMed1987

Tubular musculopleural pedicle grafting of esophageal long gaps in dogs.

Direct anastomosis of the esophagus is the treatment of choice in patients with esophageal atresia. If, however, a long esophageal gap exists, the anastomosis is performed under tension or a staged procedure is anticipated. The aim of this study was to prove that a pedicle musculopleural graft can be used to bridge the two esophageal ends. In 14 dogs through a right thoracotomy, the periosteum of the fifth rib was mobilized and the rib was excised. An intercostal musculopleural flap was created leaving the muscle attached to its vascular pedicle posteriorly with the intercostal vessels and nerve carefully preserved. A tube-like portion including pleural and intercostal muscles was formed from the free part of the graft. A 5 cm segment of the esophagus was excised and the tubular graft was interimposed. Animals were studied 1 month postoperatively with a barium meal that showed free passage through the esophageal neolumen. Peristaltic activity was studied with strain gauges above, below, and at the grafted area. Histologic examination revealed good healing at both anastomotic sites, while esophageal squamous epithelium covered the lumen all over the graft. Survival of the musculopleural pedicle graft seems to be feasible providing that its vascular supply is preserved. It is, thus, suggested that this technique might offer an alternative method in bridging long gaps in esophageal surgery.

Animals↗
PubMed1977

Esophageal atresia with tracheoesophageal fistula.

Our experience in treating ten full-term and six premature infants with esophageal atresia and distal tracheoesophageal fistula was reported. Fourteen cases were treated by a one-stage procedure and two cases by a two-stage procedure. One patient died due to pulmonary infection following the one-stage procedure and one died of septicemia after the two-stage procedure. Anastomotic stricture developed in four cases and was treated successfully by dilatation.

Esophageal Atresia↗