Biomedical subjects
Publications and source records attributed to C Musy.
A series of programs are described for use in estimating the pulmonary function of laboratory animals. Data acquisition and control are through a Hewlett-Packard (HP) 1000-F minicomputer. The system allows the estimation of respiratory parameters similar to those obtained in laboratories estimating pulmonary function in humans.
A method is described for the production of forced expirograms in anaesthetized laboratory animals, using a whole-body plethysmograph and a Hewlett-Packard (HP) 1000-F computer.
Measurements of tidal volume and breathing frequency were made in rats during a 30-min period of exposure to cigarette smoke, and were compared with those obtained during a 10-min pre-exposure period. All measurements were made in animals previously habituated to smoke exposure. Both tidal volume and breathing frequency were decreased by low-dose exposure to smoke, resulting in a 34% decrease in minute volume. At high-dose exposures (double the low-dose smoke concentration) tidal volumes showed a 23% increase over pre-exposure values with little change in breathing frequency, giving a net 20% increase in minute ventilation. This apparent inverse dose-relationship is discussed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
An interactive data input, storage, retrieval and treatment system (LAMES) is described for use in histopathological studies where pathologists evaluate tissues without any identification (termed evaluations which are 'blind'). The system produces the mean values of individual groups within an experiment, and results of statistical comparisons between the groups. The system was implemented on a Hewlett-Packard (HP) 1000-F minicomputer operating under RTE-6/VM, and was written using FORTRAN IV.