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Biomedical subjects

C Muus

Publications and source records attributed to C Muus.

6 recordsLinked to original sources
PubMed1992

Gastric pseudolymphoma. Not necessarily a benign lesion.

Gastric pseudolymphoma is thought to be a benign process. This report documents the malignant behavior of a gastric pseudolymphoma that was thought to be benign until a distant malignant B-cell lymphoma was demonstrated. Subsequent evaluation traced the B-cell lymphoma back to the gastric "pseudolymphoma." This finding stresses the relationship between gastric pseudolymphoma and gastric lymphoma, and the malignant potential of gastric pseudolymphoma. Multimodal tissue evaluation using histology, immunohistochemistry, and flow cytometry is essential. Surgical resection is the primary therapy for gastric pseudolymphoma.

Adult↗
PubMed1986

Creatine kinase variant type I in children with anoxic insult.

We evaluated 31 consecutive patients, including 11 children, with creatine kinase variants (CKV) in our laboratory during a year. All had a clinical history of central hypotonia with myocardial damage resulting in severe central hypoxia. Seven of the 11 were neonates and had Apgar scores of 2.8 (SD 2.3) at 1 min and 4.8 (SD 2.4) at 5 min, which reflected their severe birth hypoxia. For the seven neonates, the mean value for total serum creatine kinase (EC 2.7.3.2; CK) was 773 (SD 553) U/L. The mean percentage CKV was 20.7% (SD 12.5%). The other four children were being evaluated for failure to thrive; all had birth asphyxia with residual cerebral palsy and seizure activity. These older children had a lower percentage of CKV (7.3%, SD 1.01%) than did the neonates, but the total CK (725, SD 1335 U/L) was not significantly different. In four neonates there was a three- to 20-day delay in the appearance of CK variant, which followed a marked increase in total CK activity. Tissue necrosis is apparently an important factor in the pathogenesis of Type I CK variant.

Asphyxia Neonatorum↗