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Biomedical subjects

C N Harper

Publications and source records attributed to C N Harper.

2 recordsLinked to original sources

Necessity, possibility and belief: a study of syllogistic reasoning.

The present study extended the investigation of the belief bias effect in syllogistic reasoning in two ways: (1) The effect was studied under instructions to decide whether conclusions were possible, as well as necessary, given the premises; and (2) the effect was studied for types of syllogism where people rarely endorse the conclusions as well as those (valid and fallacious) where endorsements are common. Three experiments are reported, which show first that there is a marked tendency to reject unbelievable conclusions relative to abstract or neutral controls on all kinds of syllogism and under both types of instruction. There was also significant evidence of positive belief bias (increased acceptance of believable conclusions) and of interactions between belief bias effects and logical form. The results are discussed with particular respect to accounts of belief bias offered by theorists in the mental-model tradition.

Cognition↗

Optimal adaptive designs for binary response trials.

We derive the optimal allocation between two treatments in a clinical trial based on the following optimality criterion: for fixed variance of the test statistic, what allocation minimizes the expected number of treatment failures? A sequential design is described that leads asymptotically to the optimal allocation and is compared with the randomized play-the-winner rule, sequential Neyman allocation, and equal allocation at similar power levels. We find that the sequential procedure generally results in fewer treatment failures than the other procedures, particularly when the success probabilities of treatments are smaller.

Biometry↗