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Biomedical subjects

C N Hebert

Publications and source records attributed to C N Hebert.

At least 37 records · Page 2Linked to original sources
PubMed1980

Renal cysts in pigs: prevalence and pathology in slaughtered pigs from a single herd.

An abattoir investigation into kidney condemnations due to renal cysts in pork pigs from one producer showed a prevalence of 47.5 per cent. Affected pigs were the progeny of a landrace boar. Similar cysts found in a small sample of day-old piglets sired by the same boar indicated a congenital origin. A marked variation in size and frequency of cysts in the kidneys of slaughtered pigs was seen, some resembling the severity of polycystic kidneys. Histologically cysts appeared to be of tubular origin. The prevalence of affected pigs in slaughter groups from the single herd could be genetically determined. If this were so the data would be consistent with autosomal dominant inheritance. A breeding experiment to examine this hypothesis is in progress.

Animals↗
PubMed1978

The International Reference Preparations of Clostridium welchii (C. perfringens) beta and epsilon toxoids.

The Central Veterinary Laboratory, Weybridge, England was requested by the WHO Expert Committee on Biological Standardization to obtain suitable materials for international standards for Clostridium welchii (C. perfringens) beta and epsilon toxoids and to arrange collaborative assays. Preparations were obtained and dispensed as freeze-dried toxoids in ampoules. The toxoids were assayed by nine laboratories in eight countries. On the basis of the results obtained, the materials have been established as the International Reference Preparations of Clostridium welchii (C. perfringens) Beta and Epsilon Toxoids.

Animals↗
PubMed1978

International standard for anti-Brucella abortus serum: comparison of the complement-fixing activity of the first and second international standards and the EEC standard.

Although the three standards have similar agglutinating activities, it was found that the first International Standard had about half the complement-fixing activity of the second International Standard and the EEC standard. The complement-fixing activities of the latter two standards were similar. On the basis of these results, showing that the agglutination and complement-fixation tests measure different biological activities in anti-Brucella abortus sera, the WHO Expert Committee on Biological Standardization in 1976 assigned separate unitages of agglutinating and complement-fixing activity to the second International Standard for Anti-Brucella abortus Serum.

Agglutination Tests↗
PubMed1977

Bovine mycotic abortion: some epidemiological aspects.

Records from 898 cases of bovine mycotic abortion occurring over the five years 1969 to 1974 in South Wales were examined with particular reference to incidence and climate. Mean incidence was lowest in September and highest in January and February. Annual incidence of Aspergillus-type infection decreased but that of Mucortype did not alter significantly. Most abortions occurred during the last trimester of pregnancy. The abortion rate for cattle fed hay in cowsheds was extremely high compared with that for other management systems. No correlation could be detected between total rainfall or number of raindays in June and September and mycotic abortions occurring over the succeeding 12 months. Fungal abortion was followed by pregnancy in most cases where subsequent breeding performance was known.

Abortion, Veterinary↗
PubMed1977

Biochemical indicators of liver injury in calves with experimental fascioliasis.

Twenty calves were infected with 1000 metacercariae of Fasciola hepatica, the activities of 10 enzymes in plasma or serum were assayed and concentrations in serum of proteins, urea and bilirubin were determined. These values were compared with control data obtained from 14 uninfected calves. Aspartate aminotransferase, lactate dehydrogenase, sorbitol dehydrogenase, glutamate dehydrogenase, ornithine carbamoyl transferase and gamma-glutamyl transpeptidase activities increased in infected calves. Total serum protein increased, albumin decreased, globulin increased and the albumin/globulin ratio was decreased in infected calves. Plasma alanine aminotransferase, leucine aminopeptidase, alkaline phosphatase and cholinesterase activities and serum concentration of urea and bilirubin were unaffected. It was concluded that glutamate dehydrogenase and gamma-glutamyl transpeptidase were the most sensitive indicators of liver cell damage in fascioliasis.

Animals↗
PubMed1976

Estimation of the developmental age of the ovine fetus and lamb.

Fifty-six fetuses and 33 lambs were obtained from a flock of ewes at set gestational intervals between 50 to 180 days after conception. The fetuses and lambs were killed, disected and the sizes and weights of a wide range of skeletal and soft tissues were measured. Five morphological parameters emerged as most suitable for the determination of normal foetal developmental age. By plotting the mean value and ninety-five per cent tolerance limits, the rates of growth and the variability of each parameter were studied. Crown-anus length is useful for determining fetal developmental age from 50 to 100 days gestation; brain weight, long bone length and the number of appendicular ossification centres can be used to determine fetal development age from 50 days gestation until term.

Animals↗
PubMed1976

Practical application of bovine tuberculin PPD in testing cattle in Great Britain.

A national tuberculin testing trial was carried out in 8151 cattle in 132 herds due for normal herd testing and distributed throughout the 11 animal health administrative regions of England, Scotland and Wales. The numbers selected from each region were in approximately equal proportions to the total cattle populations of the regions and comprised a representative sample of the national herd. The standard intradermal comparative tuberculin test using Weybridge avian and human purified protein derivatives (PPD) was carried out on one side of the neck, and Rotterdam bovine PPD (1 X 0 mg per ml) was injected on the opposite side in the usual 'mammalian' site. Of the cattle tested, 9 X 4 per cent were classified as positive reactors to a single intradermal injection of the bovine tuberculin applying the official EEC interpretation for tuberculin tests. A single intradermal injection of human PPD would have resulted in a significantly higher proportion (10 X 4 per cent) of cattle being designated for removal. The rules of interpretation developed by Lesslie and Hebert (1975) for a comparative tuberculin test using avian and bovine PPDs, when applied to this sample, classified 0 X 80 per cent as inconclusive reactors compared with 0 X 58 per cent for the avian/human comparative test. The avian/bovine test also classified as positive reactors 0 X 12 per cent of the cattle tested, whilst the avian/human test classified as positive 0 X 05 per cent of cattle in routine herd tests during the three-year period 1972 to 1974.

Animals↗