PubMed Health⌕ Search

Biomedical subjects

C N Hebert

Publications and source records attributed to C N Hebert.

At least 73 records · Page 4Linked to original sources

International reference preparation of anti-Newcastle-disease serum.

The Central Veterinary Laboratory, Weybridge, England, was requested by the WHO Expert Committee on Biological Standardization to obtain suitable material for an international reference preparation of anti-Newcastle-disease serum for standardizing the haemagglutination-inhibition test for Newcastle disease and to arrange a collaborative assay. Ten laboratories in 10 countries assayed a batch of immune chicken serum against 2 test preparations. On the basis of the results obtained, the material has been established as the International Reference Preparation of Anti-Newcastle-Disease Serum and the International Unit of Anti-Newcastle-Disease Serum has been defined as the activity contained in 0.1734 mg of the International Reference Preparation of Anti-Newcastle-Disease Serum.

Animals↗

International reference Preparation of Newcastle Diseaase Vaccine (Live).

The Central Veterinary Laboratory, Weybridge, England, was requested by the WHO Expert Committee on Biological Standardization to arrange a collaborative assay to test a freeze-dried preparation of live Newcastle disease vaccine (Hitchner B1 strain) for its suitability to serve as an international reference preparation. Nine laboratories in 8 countries assayed the vaccine against a number of test preparations of different vaccine strains. On the basis of the results obtained, the material has been established as the International Reference Preparation of Newcastle Disease Vaccine (Live) and is considered suitable for standardizing the titration of the Hitchner B1 strain and related strains of virus.

Immunoassay↗

International standard for anti-canine-hepatitis serum.

The Central Veterinary Laboratory, Weybridge, England, was requested by the WHO Expert Committee on Biological Standardization to obtain suitable material for an international standard for anti-canine-hepatitis serum and to arrange a collaborative assay. Eight laboratories in 7 countries assayed a batch of anti-canine-hepatitis serum against 3 test preparations. On the basis of the results obtained, the material has been established as the International Standard for Anti-Canine-Hepatitis Serum and the International Unit of Anti-Canine-Hepatitis Serum has been defined as the activity contained in 0.0796 mg of the International Standard.

Animals↗

International standard for anti-canine-distemper serum.

The Central Veterinary Laboratory, Weybridge, England, was requested by the WHO Expert Committee on Biological Standardization to obtain suitable material for an international standard for anti-canine-distemper serum and to arrange a collaborative assay. Seven laboratories in 6 countries assayed a batch of anti-canine-distemper serum against 3 test preparations. On the basis of the results obtained, the material has been established as the International Standard for Anti-Canine-Distemper Serum and the International Unit of Anti-Canine-Distemper Serum has been defined as the activity contained in 0.0897 mg of the International Standard.

Animals↗

The international reference preparation of tylosin.

The Central Veterinary Laboratory, Weybridge, England, was requested by the WHO Expert Committee on Biological Standardization to obtain suitable material for an international reference preparation of tylosin and to arrange a collaborative assay. A batch of 150 g of highly purified tylosin was assayed by ten laboratories in nine countries against the tylosin standard of a commercial manufacturer. On the basis of the results obtained, the material has been established as the International Reference Preparation of Tylosin and the International Unit for Tylosin has been defined as the activity contained in 0.001 mg of the International Reference Preparation of Tylosin.

Anti-Bacterial Agents↗

The international reference preparation of hygromycin B.

The Central Veterinary Laboratory, Weybridge, England, was requested by the WHO Expert Committee on Biological Standardization to obtain suitable material for an international reference preparation of hygromycin B and to arrange a collaborative assay. A batch of 150 g of a highly purified hygromycin B was assayed in eleven laboratories in nine countries against the hygromycin B standard of a commercial manufacturer. On the basis of the results obtained, the material has been established as the International Reference Preparation of Hygromycin B and the International Unit for Hygromycin B has been defined as the activity contained in 0.0008928 mg of the International Reference Preparation of Hygromycin B.

Anti-Bacterial Agents↗

Growth rates and patterns of organs and tissues in the bovine fetus.

Ninety-two purebred Jersey fetuses from clinically normal dams derived from a variety of sources but unexposed to experimental infection, were killed between 80 and 260 days after conception and dissected to provide basic parameters of a normal population. Organs and tissues were weighed and measured and the equations for the regression of the values on fetal age evaluated. Growth followed a sigmoid curve with rapid changes in growth rate between 140 and 170 days' gestation. While a few variables increased their growth rate over the late fetal period, the majority maintained a low even rate of growth. Thyroid and cerebellum weights showed a marked reduction in growth rate at this time. Long bone length and crown-anus length were the most predictable parameters for a given gestational age.

Animals↗