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Biomedical subjects

C N Herrick

Publications and source records attributed to C N Herrick.

8 recordsLinked to original sources
PubMed1989

A national survey on preterm labor.

A national survey was conducted to examine the American obstetricians' approach to management of preterm labor. Multiple-choice questionnaires were mailed to all current members of the Society of Perinatal Obstetricians and 750 randomly selected diplomates of the American College of Obstetricians and Gynecologists. Respondents included 249 members of the Society of Perinatal Obstetricians and 441 fellows of the American College of Obstetricians and Gynecologists. Analysis of the replies reflects wide variations among American obstetricians' criteria to diagnose preterm labor, choice of tocolytic agent, use of amniocentesis, and use of corticosteroids. Significant differences were found between the two groups in many aspects of diagnosis and management of preterm labor. However, the replies reflect a high degree of awareness of and many instances of first hand experience with severe beta-adrenergic therapy complications, including maternal death. These findings emphasize the need for caution in selection of patients for beta-adrenergic tocolytic therapy and judicious use of these agents.

Adrenal Cortex Hormones↗
PubMed1981

Pulmonary maturity studies in the evaluation of premature labor.

Amniocentesis was performed in 25 patients being treated with tocolytic therapy for premature labor, in an effort to determine the incidence of patients with mature lecithin/sphingomyelin (L/S) ratios and to discover a possible effect of tocolytic therapy on pulmonary maturity studies. Optical density measurements at 650 nm (OD650) and L/S ratio determinations were performed on the amniotic fluid. Repeat amniocentesis was performed in eight patients from 48 hours to 7 days after initiation of tocolytic therapy. There was a poor correlation between OD650 values of 0.150 or greater and L/S ratios of 2 : 1 or greater (64.3% false positives); and in the eight patients who underwent repeat amniocentesis, there was no significant change in the L/S ratio.

Amniocentesis↗
PubMed1981

Amniocentesis in the evaluation of premature labor.

Amniocentesis was performed to obtain amniotic fluid for culture in 25 patients undergoing tocolytic therapy for premature labor, all of whom had intact membranes. Three specimens yielded positive cultures, 2 of which were considered contaminants. The only patient with significant bacterial growth in the amniotic fluid also had clinical signs and symptoms suggestive of amnionitis. Five of the 25 patients (20%) experienced spontaneous rupture of membranes after amniocentesis. Based on the results of this study, amniocentesis solely for the confirmation of asymptomatic amnionitis in the patient in premature labor seems to be of questionable value.

Amniocentesis↗