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Biomedical subjects

C Nagashima

Publications and source records attributed to C Nagashima.

At least 37 records · Page 2Linked to original sources
PubMed1985

Foramen magnum syndrome caused by a dolichoodontoid process.

A 21-year-old Japanese man with basilar impression with an anomalous configuration of the odontoid process and many other vertebral anomalies is reported. We thought that posterior decompression alone would be hazardous; therefore, in one session, the odontoid tip and anterior arch of the atlas were removed transorally, and posterior fixation between the occipital squama and the lamina of C-3 using acrylic plastic was performed. This treatment resulted in marked clinical improvement and required only a short hospital stay.

Adult↗
PubMed1985

Malignant change in an intradiploic epidermoid: report of a case and review of the literature.

An unusual case of intradiploic epidermoid tumor is reported. In this case, a soft mass located over the parietal bone was noted shortly after birth. The mass gradually enlarged. The tumor underwent malignant change after several excisions and repeated inflammations. The patient was successfully treated with extensive excision, radiotherapy, and chemotherapy. Compiling a summary of reported cases with a tabulation of pertinent information, we discuss the incidence, pathogenesis, prognosis, and therapy of malignant intradiploic epidermoid.

Carcinoma, Squamous Cell↗
PubMed1984

Calcium pyrophosphate dihydrate deposits in the cervical ligamenta flava causing myeloradiculopathy.

Three cases of cervical myeloradiculopathy associated with multiple calcified nodules containing identified calcium pyrophosphate dihydrate (CPPD) crystals in the ligamenta flava are described, with a comprehensive review of the 12 cases of this entity reported to date. The disease is characterized by: 1) oval or triangular areas of radiodensity in the posterior aspect of the cervical canal as seen in the lateral x-ray films and laminograms; 2) hemispherical areas of high density located almost symmetrically in the paramedial portion of the posterior spinal canal on computerized tomography scans; and 3) CPPD crystals in the nodules. It occurs independently or in association with cervical spondylosis or ossification of the posterior longitudinal ligament.

Aged↗
PubMed1984

[Evaluation of cord functions in patients with cervical radiculomyelopathy using cortical and spinal somatosensory evoked potentials].

UNLABELLED: It is desirable for neurosurgeons to be able to evaluate cord functions. To assess electrophysiologically functional status of spinal cord, cortical and spinal somatosensory evoked potentials (SEP) were studied in 33 patients with cervical radiculomyelopathy; 11 cases of cervical spondylosis, 11 cases of OPLL, 3 cases of narrow canal, 2 cases of narrow canal with OPLL, 3 cases of intradural extramedullary tumor, 2 cases of intramedullary tumor and one case of traumatic cervical cord injury. Before the operation cortical SEP was recorded from post-Rolandic area by the median nerve stimulation. Spinal SEP was recorded from the dorsal surface of the cord after partial and complete laminectomy, or before and after tumor removal. RESULTS: Cortical SEP showed abnormalities in 45% of the cases, whose abnormalities were disappearance of the early components such as P1N1 wave, P1 to P2 complex or P1 to P3 complex and delay of the peak latency. Spinal SEP showed abnormalities in 42% of the cases, and the abnormal patterns were divided into 3 groups as follows: Type 1: Slightly abnormal, P1 and N1 waves are well recorded, whereas the P2 wave is absent or markedly suppressed in the amplitude. Type 2: Moderately abnormal, the P2 wave is flat and in addition the N1 wave is diminished in the amplitude. Type 3: Severely abnormal, only the P1 wave is recorded and the N1 to P2 complex is absent. Type 1 was obtained from 3 patients, type 2 from 9 patients, and type 3 from 2 patients. Cortical and spinal SEP were closely related to deep sensations, and cortical SEP was relatively correlated with superficial sensations. There were no differences of spinal SEP in most of the cases between partial and complete laminectomy. In intradural extramedullary tumor, however, good spinal SEP was recorded in collapsed cord after the tumor removal. Clinical symptoms were improved postoperatively in 80% of patients with both normal cortical and spinal SEP. It is concluded that cortical and spinal SEP are useful for prognostic value in patients with cervical radiculomyelopathy.

Cerebral Cortex↗
PubMed1983

Craniocervical abnormalities. Modern diagnosis and a comprehensive surgical approach.

A retrospective study of 41 patients operated on between 1975 and 1983 is presented including guidelines for surgical management with some alternative technique both in anterior and posterior approaches and modern diagnostic procedures. A proposed base-line inclined--10 degrees from Reid's base-line proved to be adequate to obtain the true shape and size of the foramen magnum on CT-scan. The normal range of the clivo -axial angle in adults is reported and its clinical significance is stressed.

Adolescent↗
PubMed1982

Dense cerebellopontine epidermoid cyst.

A diffuse, bubblelike, high-density epidermoid cyst of the cerebellopontine angle is described as seen on CT scanning. The high density was attributed to high protein concentration of the cystic fluid due to a proliferative and exudative defense reaction to a "minor leak" of the lipidic material through the capsule, verified by Sudan black B stain. A description of the appearance of the tumor on computerized tomography, based on 42 cases of intracranial epidermoids reported in the literature, is discussed. To our knowledge this is the first morphological documentation of spontaneous leakage of cyst contents, and the second report in the English literature of a dense intracranial epidermoid.

Adult↗
PubMed1981

Parathyroid epilepsy with continuous EEG abnormality.

A prolonged state of unresponsiveness associated with continuous, bilaterally synchronous sharp and slow wave discharges of unusually long duration in a 31 year old male with idiopathic hypoparathyroidism was described. Diagnosis was established by determination of blood calcium, inorganic phosphorus and the Ellsworth-Howard test. The EEG abnormalities resemble those of "petit mal status" as described by Lennox and suggest a "centrencephalic epileptic manifestation."

Adult↗
PubMed1981

[Atlanto-axial, Atlanto-occipital dislocations, developmental cervical canal stenosis in the Ehlers-Danlos syndrome (author's transl)].

Clinical, biological, histopathological and laboratory data are reported on a 13-year-old male with atlanto-axial, atlanto-occipital hypermobilities, cervical canal stenosis, hypoplastic atlas and hypoplastic first rib in the Ehlers-Danlos syndrome. He developed frequent attacks of sudden tetraplegia or tetraparesis and numbness below C2 due to trivial neck injuries. Examination revealed marked hypermobilities of all joints the cutis elastica (Fig. 1), spastic tetraparesis and fasciculation of the tongue. Occipito-atlantal hypermobility measured by Wiesel and Rhothmans' method revealed 5 mm horizontal translation (Fig. 2). Anterior and lateral dislocations of atlanto-axial joints were marked due to laxicity of the joint. Posterior decompression of C1, laminotomy of C2,3, occipito-C2 fixation with autogenous iliac "board (3 X 6 cm, rectangular board) graft" yielded favorable results with 15 months follow-up. To our knowledge, this is the first patient reported with this unusual combinations.

Adolescent↗
PubMed1979

An analysis of water movement between myocardial tissue and capillary blood during reactive hyperemia.

The colloid osmotic pressure (COP) of blood from the great cardiac vein was continuously measured by means of a membrane colloid osmometer during the reactive hyperemia following temporary occlusion of the anterior descending branch of the left coronary artery in anesthetized open-chest dogs. The COP increased sharply after releasing the occlusion, then decreased below the preocclusion level before gradually returning to it. These findings indicate that a measurable amount of water moved from the capillary blood into the myocardial tissues and then flowed back slowly into the capillary blood. To analyse the factors affecting this water movement, a method is proposed in which the Starling mechanism is combined with the interstitial volume elasticity and a steady-state solution of a Navier-Stokes equation. The pressure observed with a catheter wedged into a branch of the great cardiac vein was used as a measure of capillary perfusion pressure. During the coronary arterial occlusion, the filtration constant increased while the volume elasticity of the myocardial interstitial spaces decreased rapidly. The filtration constant and volume elasticity of the interstitial space under normal conditions were approximately estimated to be 2.4 X 10(-11) cm/(sec.dyn.cm-2) and 1.1 X 10(7) dyn.cm-2, respectively.

Animals↗
PubMed1977

[Glossopharyngeal neuralgia associated with the right-bundle branch block and hypotension on sectioning a rootlet of the vagus nerve--case report (author's transl)].

A 74-year-old female who complained of severe attacks of pain in the throat and neck on the left side was first admitted to our hospital in 1971. Carbamazepine was effective at this time, and so she could be discharged. She was readmitted to the hospital in 1974 because of severe stabbing paroxysms of pain in the left throat, radiating into the auricular region as frequent as more than ten times a day. Paroxysms could not be alleviated by large doses of Carbamazepine, and side effects of the drug ensued. The pain could be easily elicited by talking, laughing, swallowing, pulling the left ear and pushing the left tragus. Block of the left 9th nerve with xylocaine produced complete relief of pain for 30 minutes to 1 hour; Plain skull X-rays and veretebral angiograms were normal. The patient was operated under general anesthesia in the sitting position. With the left suboccipital craniectomy, the left 9th nerve was cut without any change on ECG. Pulse rate, and blood pressure. Upon touching vagus nerve, the ventricular extrasystole and hypotension occurred. After the blood pressure restored to normal level and the extrasystole disappeared with administration of atropine and carnigen, the uppermost rootlet of the vagus nerve was cut. The blood pressure dropped abruptly again followed by the right bundle-branch block on ECG for approximately 20 minutes. Postoperatively, she was lethargic and had disorientation, delusion and disorientation. We attributed these symptoms to the hypoxia in operative procedure. The symptoms completely disappeared on the fifth postoperative day. The patient has been perfectly free from pain at the 15 month's follow-up without neurological or mental deficit except diminished gag reflex on the left side. We reported this our experienced case and discussed about the mechanism of the hypotension on sectioning a rootlet of the vagus nerve with literatures.

Aged↗