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Biomedical subjects

C Neuman

Publications and source records attributed to C Neuman.

6 recordsLinked to original sources
PubMed1987

Vulvar and vaginal hematomas: a retrospective study of conservative versus operative management.

We reviewed 32 cases of vulvar and vaginal hematomas treated at three hospitals in Jacksonville, Florida, from March 1975 to March 1985. Patients ranged in age from 14 to 37 years. In 29 patients the hematomas resulted from obstetric trauma and in three from other causes. We found that patients managed conservatively had more subsequent operative intervention and more complications requiring antibiotics and transfusion, and they required more days of hospitalization than patients managed operatively. We also found an increased risk of complications and increased hospitalization for patients with conservatively managed hematomas when the product of the longitudinal diameter and the transverse diameter was 15 or greater.

Adolescent↗
PubMed1982

Doxepin effects on chronic pain, depression and plasma opioids.

Thirty patients with chronic low back or cervical pain combined with clinical depression were studied in a six-week, randomized, double-blind comparison of doxepin and placebo. Dependent variables included Hamilton Depression Scores, the Clinical Global Assessment Scale, and Profile of Mood States (POMS), and subjective ratings (visual analogue scales) of pain severity, percent of time pain felt, and effect of pain on activity, muscle tension, sleep, mood, and analgesic drug consumption. Plasma levels of doxepin, desmethyldoxepin, beta-endorphin, and enkephalin-like activity were also measured. Significant improvements in the doxepin-treated group compared to the placebo group were seen in Hamilton scores, Global Assessment Scale, Profile of Mood States, percent of time pain felt, and effect of pain on sleep, muscle tension, and mood. Some improvement was observed after 1 week, although most improvement occurred at 6 weeks, when the mean doxepin dose was 2.5 mg/kg and plasma doxepin and desmethyldoxepin averaged 70 ng/ml. Nonspecific enkephalin-like activity (but not beta-endorphins) increased for the treatment group and decreased for the placebo group. The efficacy of doxepin compared with that of placebo was thus documented in several depressive and pain parameters, indicating that doxepin is a valuable treatment for patients with chronic pain and depression.

Adult↗
PubMedDate not supplied

Drinkers' use of physical availability of alcohol: buying habits and consumption level.

On the aggregate level, physical availability of alcohol is related to per capita consumption, prompting the question whether high availability can increase consumption net of social norms which enhance drinking. This issue is investigated using individual-level data in a high-availability urban environment. Effortless, efficient purchase of alcoholic beverages explains a small but significant amount of the variance in consumption when normative factors are statistically controlled. Qualitative factors of availability are discussed, with particular emphasis on food stores, which account for more than half this sample's purchases.

Adult↗