Detrusor myopathy: a cause of detrusor weakness with retention.
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Female↗
Biomedical subjects
C Nickols
Publications and source records attributed to C Nickols.
Transplacental carcinogenesis with radioactive phosphorus: the effects of promoting agents.
In a previous experiment, using 32P as a potential transplacental carcinogen in rats, we found that the isotope caused life-span shortening, reduced growth and caused ante-dating of the time of the tumour occurrence. Liver cell changes (nuclear atypia, variation in cell size) were noted and suggested liver cell damage, possible 'initiation'. A phorbol ester (TPA) and a high fat/high protein diet were used as promoting agents on further transplacentally irradiated rats. The results were identical to the previous experiment; no evidence of promotion was found.
Animals↗
Transplacental carcinogenesis with radioactive phosphorus.
1 An attempt was made to produce a model of osteogenic sarcoma using 32P transplacentally. 2 Fetal tissues appeared to be resistant to irradiation as no tumour was induced at an increased frequency in treated animals. 3 Tumours that normally occur in our strain (Sprague-Dawley rats) showed a clear tendancy to occur earlier in post-natal life in treated animals compared with controls.
Animals↗
Computer programs in histopathology record keeping.
Increasing work loads, changes in the nature of data obtained from biopsies, and the use of laboratory statistics in determining financial provision for pathological services combine to enhance the value of computer generated results and indexing in histopathology. The system described here depends on an indexed file system using the Basic Plus-2 language with a PDP-11 computer and SNOP. Error traps are included. The system is designed for secretarial use, SNOP coding being carried out by medical staff.
Computers↗