Teenage acne is influenced by genetic factors.
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Acne Vulgaris↗
Biomedical subjects
C Novac
Publications and source records attributed to C Novac.
Should CAPD be the first choice for dialysis in Romania? Audit of the Iasi 'C. I. Parhon' Dialysis Center: 1995-2000.
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Adult↗
[Is partial cystectomy a justified intervention in the treatment of bladder tumors?].
The authors present their experience of 122 partial cystectomy cases made on a number of 288 vesical tumors in our clinic, during 5 years (1986-1991) from which 23 are superficial tumors and 99 are infiltrative ones. The treatment of vesical tumors can be done in many ways; this partial cystectomy must be completed with an other therapeutic method: irradiation on chemotherapy in conformity with the anatomo-pathological form, the steady and tumoral grading.
Aged↗
[Traumatic dislocation of the peroneal tendons].
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Adult↗
[Ureterolithotomy versus retrograde ureteroscopy for lumbar ureteral stone. A cost analysis].
Ureterolithotomy is considered to be the last option for treating a lumbar ureteric stone. The authors reviewed two cases with lumbar ureteric stones treated in january 2003, one by ureterolithotomy and one by retrograde ureteroscopy regarding the costs for hospitalisation, investigations and medication. Among the certain clinical advantages for the patients, including a smaller rate of complications, ureteroscopy is considerably cheaper than open surgery. We consider that these costs criteria should be taken into consideration when the necessary equipment for-urological departments are set.
Costs and Cost Analysis↗
[Ureteral stenting after retrograde ureteroscopy. Experience of Iaşi urological department].
Ureteroscopy is a well-established procedure, which has proven the efficiency for diagnostic purposes, but mostly for ureteric stone removal. The authors describe their strategy after ureteroscopic lithotripsy with Wolf 8 Ch semirigid ureteroscope. Insertion of a double J stent for 2-4 weeks was the rule when there was an important bleeding during the procedure, the fragments were big and could not be extracted, some fragments migrated in upper third of the ureter or renal pelvis, a perforation occurred or it was found a ureteral stenosis. If the stone can be extracted without any problems (in one piece) and the ureter is normal there is no need for ureteral stenting. Having in mind that many patients describe problems with the double J stent (pains, polakiuria, etc) we recommend to insert a stent at the end of ureteroscopy only for selected cases.
Humans↗
[Caliceal stones:What did we learned after 10 years of ESWL (extracorporeal shock wave lithotripsy)].
Since its first clinical application in 1980, the indication of ESWL has rapidly extended from renal pelvis stones to almost all urinary stones. The authors discuss about their experience accumulated in the past ten years, when 476 patients with caliceal stones were treated by ESWL. The global stone free rate was 60.05%, but almost a third of the patients (where fragmentation was radiological documented after ESWL) did not returned back for control. ESWL is a good solution for superior and middle calix stones less than 1.5 cm, not very opaque, with a sufficient large caliceal width. For the stones in the lower calix, the most important criteria for success are: the stone size, the opacity and, for sure, the angle between infundibulopelvic and ureteropelvic axis.
Female↗
[Role of computerized tomography in the diagnosis of transitional cell carcinoma of the upper urinary tract].
PURPOSE: To evaluate the computed tomography (CT) semiological criteria used in the diagnosis of transitional cell carcinoma of the upper urinary tract. MATERIALS AND METHODS: 26 patients with transitional cell carcinoma of the upper urinary tract underwent preoperative CT. In all cases nephroureterectomy was performed and CT and histopathologic findings were compared. RESULTS: 16 tumors were infiltrative and 10 tumors were sessile. The smallest tumour had 7 mm diameter and the largest one 13 cm. Associated focal hydronephrosis appeared in 11 cases and diffuse hydronephrosis in 7 cases. The vast majority of these tumors (69.23%) had a 21 to 50 Hounsfield Units enhancement. CONCLUSIONS: CT is a powerful tool to diagnose transitional cell carcinoma of the upper urinary tract when data acquired in intravenous urography and echography are equivocal.
Aged↗
[Transitional cell carcinoma of the upper urinary tract- staging by computed tomography].
PURPOSE: To determine the accuracy of computed tomography (CT) in staging transitional cell carcinoma of the renal pelvis and calyces and to identify whether hydronephrosis proximal to the tumor used as a criterion for minimal invasion may improve the overall accuracy of the method. MATERIALS AND METHODS: 24 patients with transitional cell carcinoma of the upper urinary tract underwent preoperative CT. In all cases nephroureterectomy was performed and CT and pathologic staging were compared. RESULTS: Pathologic staging revealed two stage I tumors, eight stage II tumors, five stage III tumors, and 9 stage IV tumors. The initial overall CT staging accuracy was 66.66% (16 of 24 patients). Reevaluation of the CT studies by using proximal hydronephrosis as a criterion for minimal invasion improved the overall CT staging accuracy (83.33%). CONCLUSIONS: When CT demonstrates direct tumor extension through the pelvic wall, it is a sensitive indicator of high-stage tumor. Hydronephrosis proximal to the tumor may cause overstaging of stage 0-II disease.
Aged↗
[The role of intravenous urography in the diagnosis of urinary tract lithiasis in the era of new therapeutical methods].
Urinary stones continue to be an interesting and major problem for both urologists and radiologists. The authors try to present the imaging diagnosis possibilities for this pathology according to the expectations of the urologists who have to deal with urinary tract lithiasis with the new methods (extracorporeal shock wave lithotripsy, percutaneous nephrolithotomy, and ureteroscopy). Helical CT has certain advantages and in different centers in Europe appear to be less expensive than intravenous urography (IVU), but unfortunately, is not available in our medical center. So, for us, IVU remains the basic investigation for urinary stones. Echography helps a lot for correct strategy, but together with KUB cannot replace IVU if we want to avoid mistakes.
Contrast Media↗
[Can selective alpha-blockers help the spontaneous passage of the stones located in the uretero-bladder junction?].
The majority of ureteral stones at presentation in hospital are located within the distal ureter. Knowing that only half of the stones 4 to 5.9 mm will pass spontaneously, we tried to see: if we can facilitate this elimination for the stones smaller than 8 mm by selectve alpha-blockers (alfuzosin and tamsulosin) which induce relaxation of the smooth muscle of uretrotrigonal area and if there is any difference between these two drugs, concerning efficiency and tolerance. The inclusion criteria for each group were: stone size between 4 and 8 mm--even patients with steinstrasse--and previous, at least 2 weeks of expulsion treatment with nonsteroidal antiinflammatory and antispasmodic agents and Rowatinex. The results were encouraging: almost all the patients eliminated the stones without any pain in the first 5-10 days of treatment (only two patients from alfuzosin group did not tolerate this drug). We believe that both alfuzosin and tamsulosin have a crucial impact in spontaneous painless elimination of the stones smaller than 8 mm located in the uretero-bladder junction.
Adolescent↗
[Our experience in diagnostic and treatment of the upper urothelial tract tumours].
UNLABELLED: The aim of the study was to analyse methods of diagnostic and treatment used in our clinic in patients with upper urothelial tract tumors in recent years. MATERIAL AND METHODS: We studied retrospectively 117 files of patients diagnosed with upper tract tumors between 1996-2002. RESULTS AND DISCUSSIONS: The diagnostic was based in 99 cases by urography, retrograde pyelography or both, in 10 cases by cystoscopy (for intramural ureteral tumors), in 8 cases by ureteroscopy and one case was diagnosed by antegrade pyelography. Ultrasound didn't diagnosed solely any tumor. Computerized tomography was also be helpful for staging. Radical treatment was realised in 73 patients (total nephroureterectomy), in 4 patients ureterectomy of the ileo-pelvic segment were realised by stripping. In 20 patients, we performed subtotal nephroureterectomy, in 9 patients transurethral resection, in 2 cases terminal ureterectomy, and in one case we done endoscopic electrocauterization after cold biopsy. CONCLUSION: The most important paraclinical investigation in diagnostic of upper urothelial tract tumors are radiological investigations, urography and retrograde pyelography. Best way to cure such tumors are total nephroureterectomy. In select cases we can perform terminal ureterectomy and transurethral electroresections.
Adult↗
The morphologic changes induced by hormone and radiation therapy on prostate carcinoma.
The morphologic changes induced by hormone and radiation therapy were evaluated in prostate biopsy and prostatectomy specimens from patients with residual prostate carcinoma. The two therapeutic methods induce changes both in the nonmalignant and malignant residual prostatic tissue. Following hormone therapy, the nonmalignant prostatic tissue showed atrophy of prostatic acini associated with fibrosis, basal cell hyperplasia, degenerative changes of the secretory epithelial cells, and a marked decrease of high-grade intraepithelial neoplasia (HGPIN). In the fragments of residual carcinoma, squamous cell metaplasia, necrosis, and necrobiosis in the foci, vacuolization of the cell cytoplasm, smaller, rare nucleoli, intraluminal crystalloids, higher Gleason score associated with a lower capsular penetration, areas of necrosis and mitoses were found. Following radiation therapy, the nontumoral prostatic tissue showed an increased number of atrophic acini, squamous cell metaplasia, and presence of atypical glands. The morphologic changes induced by radiation therapy in the residual prostatic carcinoma were characterized by an abnormal architectural structure of the glands and presence of cell atypias correlated with the biochemical lowering of serum PSA.
Androgen Antagonists↗
[Descriptive epidemiologic study of nosocomial infections in "C.I. Parhon" hospital of Iaşi].
Nosocomial infections (NI) represent a major public health problem. The descriptive study was carried out during one year, based on a lot of 12,731 in-patients from "C.I. Parhon" hospital. The objectives of the study were assessment of NI incidence and risk factors as well as monitoring resistance to antimicrobial drugs of bacterial pathogens from the hospital. The results of the study show lower NI incidence rates: 0.27%, most of them (91.5%) being urinary tract infections in the age group 65 y and over. 42.8% of cases were associated with risk factor of diabetes mellitus, neoplasm, skin or cardiovascular chronic conditions. The main etiological agent found for the NI was pseudomonas pyocyanea resistant to antibiotics. The antibiotic sensitivity analysis for the other gram negative rods illustrates gradually acquired resistance to the third or fourth generation of cephalosporins.
Adult↗
[Tumors of the upper urinary tract. Apropos 35 cases].
Thirty-five cases of upper urinary tract tumors treated by the authors in an interval of 10 years (1979-1988) are presented. After a detailed analysis of the cases some general considerations on the anatomopathologic forms of upper urinary tract tumors, stage classification, symptoms and clinical and laboratory diagnosis, therapeutical indications are made.
Adult↗
[The therapeutic approach in superficial epithelial tumors of the bladder. Apropos 98 cases].
Between 1985 and 1990, superficial epithelial tumors of gallbladder were found in 98 patients. Peculiar aspects such as age, sex, symptoms, clinical and laboratory diagnosis, surgical treatment, additional interventions, postoperative treatment, anatomo-pathological examination, pTNM classification and tumoral grading, postoperative recurrences, occurring after the primary and adjuvant treatment, were analysed. After some general comments, the authors point out that in their experience the lowest rate of postoperative recurrences was obtained by a multimodal treatment, that is surgery and vesical instillations with cytostatics or B.C.G. vaccine, according to EORCT scheme.
Adult↗
[The present-day aspects of urogenital tuberculosis. Comments on 113 cases].
One hundred and thirteen new cases of urogenital tuberculosis, admitted and treated in the interval 1980-1986 (an average number of 16 cases yearly) are reported. The analysis of these patients includes age, sex, bacillary history, symptoms, clinical forms, diagnostic methods, therapeutical management and late results. Seven cases are detailed. It is concluded that the treatment with the actual tuberculostatic drugs is efficient provided the urogenital tuberculosis is early detected. In case this disease is late detected the treatment is associated, drug and surgical.
Adult↗
[Malignant infiltrating bladder tumors. Comments on 157 cases].
157 cases of malignant infiltrative tumors of urinary bladder admitted and treated in a 5-year interval (1983-1988) are presented. Considerations on age, sex, urological history, associated urological disorders, symptoms and clinical examination, diagnostic methods, surgical procedures and their association with other non-surgical procedures, postoperative evolution, pathological examination of the resection sample, tumoral stage, recurrences are made. Five cases treated by various methods are presented in detail. The clinical and laboratory diagnosis, therapeutical methods and the staged therapeutical indications are also commented upon. In the malignant infiltrative tumors of urinary bladder the authors recommend the partial cystectomy which, when correctly indicated and performed, gave similar results as total cystectomy. It is also underlined that in case of an urographically silent kidney the attitude should be conservative and the treatment of the malignant infiltrative tumors of urinary bladder should be multimodal.
Aged↗