PubMed Health⌕ Search

Biomedical subjects

C Nunez

Publications and source records attributed to C Nunez.

At least 37 records · Page 2Linked to original sources
PubMed1986

Fine-needle aspiration biopsy of the pancreas: a study of 61 cases.

Eighty-six fine-needle aspirates (FNAs) of pancreas from 74 patients were reviewed. Histological confirmation or clinical follow-up of the final diagnosis was available in 61 aspirates from 49 patients. Of 42 proven malignant cases, FNAs were diagnosed as positive in 21 (50%), suspicious in 4 (9.5%), negative in 12 (28.6%), and unsatisfactory in 5 (11.9%). Of 19 proven benign cases, FNAs were diagnosed as negative in 15 (78.9%) and unsatisfactory in 4 (21%). This resulted in a 50% sensitivity, a 100% specificity, a diagnostic efficiency of 59%, a predictive value of a positive test of 100%, and a predictive value of a negative test of 55.6%. Thirty-six primary pancreatic adenocarcinomas and six metastatic tumors to the pancreas were encountered. Benign cases were attributed to anatomical pancreatic variants, acute pancreatitis, abscess, chronic pancreatitis, and pseudocysts. Pancreatic FNA was safe, accurate, and relatively inexpensive, but it was relatively insensitive in the diagnosis of malignancy.

Adenocarcinoma↗
PubMed1985

Malignant placental site trophoblastic tumor.

Placental site trophoblastic tumor is a rare variant of trophoblastic disease. The malignant form of this disease with metastasis and death is even more infrequent, as is evident from only five cases in the literature. A 30-year-old black woman who died from this disease is presented. Patients with metastases are at extremely high risk with no reported survivors and must be treated aggressively with chemotherapy and cytoreductive surgery. This type of trophoblastic tumor apparently exhibits a different biologic behavior as compared with choriocarcinoma.

Adult↗
PubMed1984

Fine-needle aspiration biopsy in a pediatric population. Report of 64 consecutive cases.

Fine-needle aspiration biopsy for diagnosis of mass lesions has seldom been used in pediatric patients. Sixty-four aspirations from pediatric patients have been reviewed in order to determine the adequacy of this technique in the pediatric age group. There were 38 benign diagnoses, 19 malignant diagnoses, and 7 unsatisfactory specimens. The benign diagnoses included inflammatory lesions, benign tumors, cystic lesions, and miscellaneous lesions. The malignant diagnoses included neuroblastomas, leukemias or lymphomas, small cell or poorly differentiated tumors, Wilms' tumors, rhabdomyosarcomas, a Ewing's sarcoma, and a postirradiation fibrosarcoma. Correlation of histologic and cytologic diagnoses was possible in 53 cases. The diagnostic sensitivity and specificity for the detection of malignant disease were 76% and 100%, respectively. These results suggest that fine-needle aspiration biopsy is a useful technique in the diagnosis of pediatric mass lesions.

Abdominal Neoplasms↗
PubMed1983

Ovarian rhabdomyosarcoma presenting as leukemia. Case report.

A condition of pure ovarian rhabdomyosarcoma in a 16-year-old female is described. The tumor presented with a leukemia-like picture, with extensive peripheral blood and bone marrow involvement which led to an initial diagnosis of acute lymphoblastic leukemia. The diagnosis was achieved at autopsy and was supported by ultrastructural findings of Z-band-like material and alternating thin and thick filaments.

Adolescent↗
PubMed1983

Biopsy needle characteristics assessed in the laboratory.

Radiologists are frequently called upon to perform percutaneous biopsy. Selection of the proper needle is becoming more complex as the number of types increases and reports of better results with certain needles proliferate. The authors evaluated a wide variety of needles of different caliber, cutting tip, and bevel. Using a standard biopsy technique for in vitro specimens, the samples were analyzed quantitatively by precise weight measurement and qualitatively by cytopathological means. It was concluded that large-bore needles were superior to "skinny" needles, and small-bore needles having an acute bevel angle were superior to flat-bevel needles of similar gauge in terms of specimen size and preservation.

Biopsy, Needle↗
PubMed1983

Psammoma bodies in the cervicovaginal smear in association with a papillary tumor of the peritoneum.

Psammoma bodies and abnormal cells were identified in the cervicovaginal smear of a 27-year-old woman. This rare finding aided in the diagnosis of papillary tumor of the peritoneal cavity in this asymptomatic patient. These findings stress the importance of recognizing that psammoma bodies do appear exclusively in adenocarcinoma of the ovary. Their presence should alert the observer to the possibility of a benign, reactive, or malignant process in the peritoneal cavity.

Adenocarcinoma↗
PubMed1981

Lennert's lymphoma presenting with clusters of cutaneous infection.

We recently diagnosed and studied a case of Lennert's lymphoma in a young black man who presented with a chronic pyoderma and multiple cutaneous infections of viral origin. Lennert's lymphoma, or malignant lymphoma with a high content of epithelioid histiocytes, is an uncommon variant of non-Hodgkin's lymphoma. This report highlights the role of idiopathic immunosuppression in lymphoma patients.

Adult↗
PubMed1979

Histological reaction to percutaneous epidural neurostimulation: initial and long-term results.

Percutaneously inserted spinal epidural neurostimulation has been derived as a simplified safe alternative to surgically implanted, dorsal column stimulation that is used in the effective treatment and control of spasticity and intractable pain. Twenty-seven tissue specimens from fifteen patients having had percutaneous epidural neurostimulation systems implanted were studied with the aid of light microscopy. The biopsies from tissues around the cables, around the receivers, and at the actual site of epidural stimulation (at the metallic contact), were studied at time intervals varying from one week to two years postimplantation. Long-term results, which only show dense fibrous encapsulation of the cables and the receiver, substantiate clinical belief regarding the "histological safety" of this electronic modality.

Electric Stimulation Therapy↗
PubMed1979

Neurogenic tumors of the brachial plexus: report of two cases.

Two cases of solitary neurogenic tumors of the brachial plexus unassociated with von Recklinghausen's disease are presented. One patient had a malignant schwannoma. The lesion of the other patient was benign and was diagnosed pathologically as a plexiform neurofibroma. These uncommon neurogenic tumors of the brachial plexus unassociated with von Recklinghausen's disease pose diagnostic and surgical problems. The initial clinical presentation is usually that of a painless supraclavicular mass. At the time of surgical exploration, the exact site or nerve of origin cannot always be identified. If motor loss is caused by such a tumor of the brachial plexus, it usually indicates a malignant lesion and a poor prognosis. Although wide radical excision of a malignant neurogenic tumor is indicated surgically, one of our patients had an early malignant recurrence that necessitated immediate amputation.

Adult↗
PubMed1979

An unusual neoplasm of adipose tissue in a rat.

The light microscopic features of a spontaneous neoplasm of adipose tissue from a rat were suggestive of a mixed liposarcoma with a myxoid matrix. However, ultrastructurally, the cell characteristics were those of a hibernoma. These characteristics included cells containing lipid droplets of variable size, numberous pleomorphic mitochondria and close apposition to blood vessels. Lipofuscin granules and subplasmalemmal condensations were not observed ultrastructurally.

Adipose Tissue↗