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Biomedical subjects

C Ozturk

Publications and source records attributed to C Ozturk.

13 recordsLinked to original sources

Involuntary movements in infantile cobalamin deficiency appearing after treatment.

Involuntary movements may be a symptom in most infants who present with neurologic syndrome of infantile cobalamin (vitamin B12) deficiency. In this report, two infants with cobalamin deficiency are presented. These patients also developed a striking movement disorder that appeared a few days after treatment with intramuscular cobalamin. The movement disorder was characterized by severe involuntary movements, which were a combination of tremor and myoclonus particularly involving tongue, face, pharynx, and legs. The neurologic symptoms improved within a few days after the administration of clonazepam. In each patient the mother was also cobalamin deficient and the infant was solely breast-fed. The cause of involuntary movements that can appear rarely after treatment in infantile cobalamin deficiency is not known. Besides initial neurologic presenting symptoms of cobalamin deficiency, the occurrence of involuntary movements after treatment should also receive attention. This movement disorder may disappear spontaneously, or an additional treatment may be an alternative approach if the symptoms are severe.

Anticonvulsants↗

Four-dimensional B-spline based motion analysis of tagged MR images: introduction and in vivo validation.

In MRI tagging, magnetic tags-spatially encoded magnetic saturation planes-are created within tissues acting as temporary markers. Their deformation pattern provides useful qualitative and quantitative information about the functional properties of underlying tissue and allows non-invasive analysis of mechanical function. The measured displacement at a given tag point contains only unidirectional information; in order to track the full 3D motion, these data have to be combined with information from other orthogonal tag sets over all time frames. Here, we provide a method to describe the motion of the heart using a four-dimensional tensor product of B-splines. In vivo validation of this tracking algorithm is performed using different tagging sets on the same heart. Using the validation results, the appropriate control point density was determined for normal cardiac motion tracking. Since our motion fields are parametric and based on an image plane based Cartesian coordinate system, trajectories or other derived values (velocity, acceleration, strains ...) can be calculated for any desired point within the volume spanned by the control points. This method does not rely on specific chamber geometry, so the motion of any tagged structure can be tracked. Examples of displacement and strain analysis for both ventricles are also presented.

Algorithms↗

Turkish children's performance on Denver II: effect of sex and mother's education.

One thousand and ninety-one healthy Turkish children were tested with the Denver II developmental screening test and the data were analysed for sex and sociocultural differences. Few and inconsistent differences were observed between boys and girls. On the other hand, there were marked differences between sociocultural groups, particularly in terms of fine motor and language areas and in older preschool children. The effect of maternal education on the child's development is more important in countries where preschool education is not commonly available. Whether this effect diminishes after 1 or 2 years of schooling is to be investigated.

Child Development↗

Measurement of wound healing by image analysis.

Chronic wound healing is a major health problem consuming more than $10 Billion/year. Noninvasive measurements of wounds are critical for evaluation of different therapies. In this paper, we present two image processing methods which can be used to compare the effects of different dressings on pig skin wounds. In the first part, the healing process is monitored by area measurements. Using thresholding the wound areas are calculated by pixel counting and corrected with perspective scaling. This technique showed good correlation with manual area measurements. In the second part, 3 D coordinates of the selected wound points are calculated using triangulation from a single colored image coordinates. Such a 3 dimensional image reconstruction from a single camera is made possible by projecting a structured light pattern onto the skin. In this study, a unique pattern consisting of colored dots is used. This color-coded pattern provides many advantages over widely used grid patterns: it is not necessary to see the whole image to recognize the points, since every dot can be identified correctly from its closest eight neighbors, eliminating occlusion problems. Our approach to structured light also mitigates the problem of motion in a subject, since all the coding information is contained in a single image.

Animals↗