Interview: Cynthia Porter Hartman.
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Operating Room Nursing↗
Biomedical subjects
C P Hartman
Publications and source records attributed to C P Hartman.
E. coli DNA polymerase I: enzymatic functions and their application in polymer formation, nick translation and DNA sequencing.
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Base Sequence↗
Production of a mutagen from ponceau 3R by a human intestinal anaerobe.
Ponceau 3R was reduced in vitro by Fusobacterium sp. 2, a human intestinal anaerobe, to a product which is mutagenic when metabolically activated by liver S9 preparations in the Salmonella/mammalian-microsome mutagenicity test. This mutagenic metabolite has been identified as 2,4,5-trimethylaniline.
Aniline Compounds↗
Azo reduction of trypan blue to a known carcinogen by a cell-free extract of a human intestinal anaerobe.
The azo reductase activity of a cell-free extract of Fusobacterium sp. 2 is characterized using trypan blue as a substrate. Either chemical reduction of this dye with sodium hydrosulfite or reduction by the cell-free extract produces a mutagenic product, o-tolidine. The o-tolidine is mutagenic in the Ames Salmonella/mammalian-microsome mutagenicity test when activated by a rat liver S9 preparation.
Benzidines↗