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Biomedical subjects

C P Muth

Publications and source records attributed to C P Muth.

14 recordsLinked to original sources

Laparoscopy of a traumatic rupture of a dysontogenetic splenic cyst. A case report.

The role of laparoscopy in the stepped approach to the diagnosis and treatment of blunt abdominal trauma has not yet been fully elucidated. Despite the use of a variety of imaging modalities, it can still be difficult to make a proper evaluation in cases where there are questionable abdominal injuries. In particular, when there is a discrepancy between a bland clinical picture and the results of diagnostic imaging procedures, laparoscopy should be given preference over laparotomy, provided the patient's circulatory situation is stable. Herein we describe a case in which laparoscopy allowed the detection and treatment of a traumatic rupture of a dysontogenetic splenic cyst that had mimicked a rupture of the spleen on both the ultrasound (US) and computed tomography (CT) images.

Abdominal Injuries↗

[Value of mammography and ultrasound in diagnosis of breast carcinoma].

The assessment of the value of mammography and ultrasound studies of the breast was the aim of this work. Mammography has consistently demonstrated its value as a good screening method, but also in the differentiation between several diagnoses. The sensitivity of the mammography is high with 85% to 90%. The specificity should be considered critically and can't be used in every case. But the use of additional methods of the mammography sometimes arrives more information. Therefore the mammography is the basic method for detection of early clinically occult cancer. Advantages of ultrasound are the better differentiation of cysts from solid lesions and the dissolution of dense breast masses in the mammography. However the mammary ultrasonography has more limitations than mammography. Some different kinds and materials for improving ultrasound are high resolution or colour Doppler ultrasound and the using of ultrasound contrast agent. At present mammasonography seems to be the most important additional method behind mammography.

Breast Neoplasms↗

Iopentol (Imagopaque) in vascular procedures. A multi-centre monitoring trial assessing adverse events and diagnostic information--results from 3,587 patients in Germany.

The aims of the present open, non-comparative survey were to study the safety and efficacy of iopentol (Imagopaque, Nycomed Imaging AS, Oslo, Norway) in a large patient group. In a series of German centres, 3,587 patients underwent various contrast-enhanced examinations with iopentol. The most frequent examinations were computed tomography (CT) (1,740), phlebography (462), and digital subtraction angiography (DSA) (493). Only 82 patients (2.3%) experienced one or more adverse events. Sixty-one (1.7%) of these events were possibly or probably caused by the contrast medium. A total of 111 adverse events were registered, 54 of mild, 42 of moderate and 12 of strong intensity, and 51 events required treatment. The most frequent adverse events were nausea (34), erythema (14) urticaria (9), taste sensation (6), circulatory reactions (5) and angina pectoris (5). The frequencies of adverse events were 2.9% in CT, 2.0% in DSA, 2.0% in phlebography, 1.6% in cardioangiography, and 0.4% in urography. Patients with arteriosclerosis, an earlier contrast medium reaction, multimorbidity or age over 70 years had a statistically significantly higher risk of experiencing an adverse event. Patient tolerance was very good; the mean score was 83% on a visual analogue scale (VAS) ranging from extremely bad (0%) to extremely good (100%). Efficacy, as measured on VAS, was determined. Technical quality was scored as 80%, contrast enhancement within the vessels as 80% and delineation of lesions as 79%. The results from this large patient population confirms the experience from clinical practice that iopentol is a safe, well tolerated and efficient contrast medium.

Angiography, Digital Subtraction↗