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Biomedical subjects

C P Newman

Publications and source records attributed to C P Newman.

12 recordsLinked to original sources

An outbreak of waterborne cryptosporidiosis associated with a public water supply in the UK.

In November and December 1992, an outbreak of waterborne cryptosporidiosis occurred in Bradford, a city in the North of England. In all 125 cases were involved, the majority of whom lived in part of the city which received its drinking water supply from a single water treatment works. A case control study demonstrated an association between illness and the consumption of tapwater from this source; those drinking large volumes being more likely to have been ill. Treated water from the defined source yielded cryptosporidial oocysts. Heavy rainfall was recorded in the catchment area of the reservoir supplying raw water to the treatment works, immediately prior to the probable time of infection, based on dates of onset of illness.

Adolescent↗

Surveillance and control of Shigella sonnei infection.

Shigella sonnei infection continues to present a challenge to those responsible for the control of communicable disease. It is readily passed from one person to another by faecal-oral spread, particularly in children. Traditionally, control measures have emphasised hygienic precautions and exclusion of infected individuals from schools and nurseries. The extent to which these measures have been effective appears to be limited. This review of the literature and recent epidemiological data was conducted to identify interventions which contribute to the control of the infection without unjustifiably restricting the freedom of individuals.

Dysentery, Bacillary↗

Verotoxin producing Escherichia coli O 157 infections associated with the consumption of yoghurt.

Sixteen cases of verotoxin producing Escherichia coli (VTEC) O 157:H7 Phage Type 49 infection were identified in the North West of England from 1 September to 1 November 1991, eight of whom lived in or around the same large town. Eleven of the cases were aged 10 years or less, and five of the affected children developed haemolytic uraemic syndrome. A case control study demonstrated a strong association between VTEC O 157:H7 PT 49 infection and the consumption of a locally produced live yoghurt. This is the first time that an outbreak of VTEC O 157 infection has been linked to the consumption of yoghurt and this vehicle of infection should be considered when investigating such outbreaks in future.

Adolescent↗

Hazardous incidents and immunity to hepatitis B.

In the period March 1989 to October 1990, Leeds Public Health Laboratory received reports of 2975 needlestick and similar incidents involving National Health Service staff where there was a risk of transmission of hepatitis B virus. Despite an active immunisation programme in the hospitals where staff worked, 50% of those involved showed no evidence of immunity. In reviewing their immunisation programmes, health authorities should take account of those groups of staff who are at risk of exposure and ensure that all those included in the programme are encouraged to take up the offer of immunisation.

Accidents, Occupational↗

A prolonged outbreak of ornithosis in duck processors.

In 1985 an outbreak of ornithosis affected 13 of 80 (16%) workers in a duck-processing plant. New employees were three times more likely to become cases than established employees. The highest attack rate was in those on the production line. Following the outbreak, an occupational health scheme was set up to monitor the health of new recruits to the company. Serological evidence of recent infection was demonstrated in 18 of 37 (49%) new employees tested in the first 3 months of employment. Five (14%) also had clinical evidence of ornithosis. Veterinary investigation of the ducks demonstrated a high proportion with asymptomatic chlamydial infection. It is suggested that ornithosis may be more common in duck processors than is currently supposed. Strategies to reduce occupational risks are discussed.

Abattoirs↗

Re-evaluation of viability testing of cadaveric kidneys for transplantation.

Twenty-three human cadavers kidneys were studied during hypothermic pulsatile perfusion prior to transplantation. The accumulation of laevo-lactate and lactate dehydrogenase, alterations in pH and perfusion flow rate were measured and compared with organ function following transplantation. No parameter measured was found to be an accurate index of potential function.

Cadaver↗