PubMed Health⌕ Search

Biomedical subjects

C P Perry

Publications and source records attributed to C P Perry.

24 records · Page 2Linked to original sources

Successful management of pregnancy-induced pancytopenia.

The 46th case of known pregnancy-induced pancytopenia is reported. Pregnancy may play an etiologic role in this rare condition, but the specific mechanism is unknown. Maternal mortality is 63%, and fetal and neonatal wastage is 46%. The patient reported is a 24-year-old Oriental woman who delivered a healthy female infant. Her survival is attributed to conservative management with carefully timed packed cell and platelet transfusions.

Adult↗

Placenta previa and preeclampsia complicating the management of renal transplant patients.

Presented are three patients who have delivered full-term normal infants after renal transplants from living related donors. One patient had a placenta previa with excessive vaginal hemorrhage. Another patient manifested preeclampsia. Management of these and other complications should be aggressive and thorough with special precautions taken to preserve graft function. In our patients, pregnancy was not harmful to the renal transplant. No fetal complications from immunosuppressive drugs were noted and the patients' dosage requirements did not change. Counseling regarding family planning is essential in patients with renal transplant.

Adult↗

Intrauterine growth retarded infants. Correlation of gestational age with maternal factors, mode of delivery, and perinatal survival.

Fifty-eight infants of 3332 deliveries (1.7%) were found to be growth retarded (IGR) at birth. For purposes of analysis, the infants were divided into 2 groups according to gestational age at delivery: Group I infants were delivered between 38 and 43 weeks' gestation, and Group II infants were delivered between 28 and 37 weeks'. The infants at greatest risk are those who manifest chronic intrauterine fetal distress associated with prematurity. Asphyxia was evident in 9 of 19 infants (47%) in Group II as compared to 9 of 36 infants (25%) in Group I. The premature IGR infants delivered by low forceps and cesarean section had higher 1- and 5-minute Apgar scores than those delivered spontaneously. There was a five-fold increase of intrauterine demise and a two-fold increase of neonatal deaths in Group II IGR infants as compared to the non-IGR premature infants. In the management of IGR, a combined obstetric-pediatric approach is important. A higher index of suspicion, appropriate evaluation, earlier diagnosis, and expedient delivery are essential if the prognosis for an IGR infant is to be improved.

Apgar Score↗

Treatment of irradiation injury to the ureter by ileal substitution.

Ureteral obstruction following radiotherapy for cervical cancer is most often due to recurrent tumor. However, in a few patients ureteral stricture is secondary to radiation damage. Surgical treatment of this obstruction requires special consideration since many procedures for urinary diversion may be contraindicated in an irradiated pelvis. Ileal substitution (uretero-ileoneocystostomy) preserves renal function without resorting to external diversion of urine. A discussion of the method together with a report of 6 patients treated in this manner is presented. Results were excellent, with followup ranging from 11/2 to 4 years. A brief history of irradiation damage to the ureter and the use of small bowel as substitute ureter is discussed. Patient acceptance of this surgical approach was gratifying.

Adult↗

Current concepts of pelvic congestion and chronic pelvic pain.

Chronic pelvic pain in women is a common and disabling illness caused by numerous organic pathologies usually accompanied by varying psychological dysfunctions. Many patients may receive misdiagnosis, misdirected therapies, or do not seek help at all. Pelvic congestion may be responsible for pain in patients without more common diseases, such as endometriosis and pelvic adhesions, among others. Our view of this condition is evolving. In the United States, this medical condition remains controversial. More recent research from the United Kingdom has caused a fresh look at the diagnosis and treatment of chronic pelvic pain produced by pelvic congestion. Potentially, many patients may benefit from a reconsideration of this approach.

Chronic Disease↗