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Biomedical subjects

C P Wilson

Publications and source records attributed to C P Wilson.

11 recordsLinked to original sources

Social work and organ transplantation.

The nonsurgical aspects of organ transplantation are complex and beyond the expertise of professionals of any one discipline. This article addresses some of the issues involved in the organ donation, procurement, and transplantation process and suggests roles that social workers can play at the societal, institutional, and case levels in this new area of health care. Social workers can advocate against the commercialization of organ transplantation; help educate the public regarding organ donation; foster approaches to donor allocation that are free of social worth considerations; provide support to the families of organ donors before, during, and after the decision; and assist families to accept completely the death of their loved one. Through such services, social workers can free medical staff to focus on medical areas of organ transplantation and ensure that organ donation remains a humane and humanized gesture.

Family↗

Abstaining and bulemic anorexics. Two sides of the same coin.

This article presents a psychodynamic approach to the understanding and treatment of abstaining and bulemic anorexics. While the abstainer starves herself to the point of emaciation and the bulemic may gorge to the point of obesity, the underlying emotional conflicts of the two groups of patients are the same. The ego (character structure) of the bulemic is not as perfectionistic and rigid as that of the abstainer, so the patient is periodically overwhelmed not only by impulses to gorge but also by impulses of all kinds. A description of the clinical syndrome, the physiological findings and details of the laboratory diagnosis of anorexia nervosa are provided. Family psychodynamics which are viewed as etiologic are presented. A psychodynamic therapeutic approach is described and examples of the treatment of an abstaining and bulemic patient are detailed. The crucial therapeutic role of the family physician is explored with emphasis on the importance of the physician's encouraging the patient to bring up questions about food and eating with the psychiatrist because such preoccupations mask other conflicts.

Adolescent↗

Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells.

A clonal hamster beta cell line (HIT) was established by simian virus 40 transformation of Syrian hamster pancreatic islet cells. Cytoplasmic insulin was detected in all cells by indirect fluorescent antibody staining, and membrane-bound secretory granules were observed ultrastructurally. Acidified-ethanol extracts of HIT cell cultures contained hamster insulin as determined by radioimmunoassay, radioreceptor assay, and bioassay. One subclone at passage 39 contained 2.6 micrograms of insulin per mg of cell protein. [3H]Leucine-labeled HIT insulin and proinsulin were identical to islet-derived proteins when compared by NaDodSO4/polyacrylamide gel electrophoresis of immunoprecipitates. HIT cell insulin secretion was stimulated by glucose, glucagon, and 3-isobutyl-1-methylxanthine. Insulin secretion at optimal glucose concentration (7.5 mM) was 2.4 milliunits per 10(6) cells per hr. Somatostatin and dexamethasone markedly inhibited HIT insulin secretion. The HIT cell line represents a unique in vitro system for studying beta cell metabolism and insulin biosynthesis.

Animals↗

The fear of being fat and anorexia nervosa.

It was found in the analysis of patients with anorexia nervosa that when they resumed normal weight and began menstruating again, analysis focused on their complex and pathological body image, which was manifested consciously by an intense fear of being fat. Scrutiny of nonanorexic women in analysis showed them to have a less intensely cathected fear of being fat or body-image disturbance, and observation and questioning of normal women in our culture showed many of them to also have this fear. Unconsciously caused by their feminine identification, many male homosexuals and men with severe latent homosexual conflicts were found to have the fear of being fat, in contrast to other men who do not evidence the fear. The fear of being fat is greatly overdetermined, and clinical material is presented to demonstrate that conflicts from every level of development--pre-Oedipal, Oedipal, adolescent, and adult--are displaced onto and masked by the fear.

Anorexia Nervosa↗

Parental overstimulation in asthma.

A discussion of "The Role of Primal Scene and Masochism in Asthma," by Cecilia Karol, M.D. The author presents case material corroborating Dr. Karol's hypotheses about the role of primal scene exposure and sadomasochistic fantasies in asthma and which documents the thesis that primal scene is a part of a global pattern of parental overstimulation which in the pregenital maturational phases establishes the predisposition to develop asthma. He further confirms Melitta Sperling's hypothesis that unconscious conflicts of the mother or father predispose a child to the development of psychosomatic disease and that specific parental habits and fantasies involving the lungs determine the choice of the respiratory system for symptom formation.

Adolescent↗