[The exercise test in variant angina].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to C Pandullo.
Explore the source record for details and available documents.
Health education still lacks content and represents an undefined field. Nevertheless, it may be a cheap, simple and reliable tool to offer the public, thus giving them knowledge concerning the prevention and the treatment of and the rehabilitation from heart disease. Different strategies are available, but it is of paramount importance for physicians and nurses working in the field of cardiology, to change their attitude in approaching patients and to have specialized training. Numerous post-graduate courses dealing with new diagnostic and therapeutic procedures are continuously conducted in our Country. On the contrary, very little has been done to stimulate medical staff to be interested in acquiring knowledge of prevention and health education methodology and practice. Health policy should therefore be directed to this goal, and the performance of the Centres of Cardiology might be augmented with the help of volunteer organizations.
Explore the source record for details and available documents.
The finding of ST segment depression (reduced ST) in the anterior leads during acute inferior myocardial infarction is a common clinical sign. Nevertheless, its significance is not yet well established. To evaluate the significance of this finding, 58 patients with acute inferior myocardial infarction, who has an electrocardiogram within 8 hours from the onset of the disease, were divided into 2 groups: group A (14 patients with anterior reduced ST less than 1 mV) and group B (44 patients with reduced ST greater than or equal to 1 mV in one or more anterior leads). All patients subsequently underwent coronary angiography and left ventriculography, mean 50 days after acute myocardial infarction. reduced ST was not predictive of left anterior descending coronary artery disease. On the contrary, a significantly higher rate of 2-3 vessel disease (p less than 0.05) and of critical stenosis or occlusion of the right or circumflex coronary artery (p less than 0.05) was found in group B. Peak CK level was significantly higher (p less than 0.01) in this group as well. No significant difference was found in ejection fraction and anterior wall motion abnormalities, whereas a higher number of patients in group B showed a depressed function of the postero-basal segment (p less than 0.05). During 6 months follow-up, 2 patients in group A and 24 in group B experienced cardiac events (angina, reinfarction, heart failure, coronary artery by-pass grafting, cardiac death) (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
To determine whether exercise testing performed soon after myocardial infarction may predict the degree of coronary artery disease, 78 patients performed stress testing and coronary angiography 15 +/- 5 and 64 +/- 35 days, respectively, after myocardial infarction. Out of 34 patients with a positive test, 22 (65%) demonstrated a multivessel disease, and 37 (84%) out of 44 patients with a negative test had normal coronary angiograms or single vessel disease (p = .0006). In addition to stress testing, no clinical parameter considered (infarct location, heart failure and cardiomegaly) was predictive of the extent of coronary artery disease.
We report upon a patient with mitral valve prolapse of mild degree who complained of paroxysmal tachyarrhythmias after drinking ice-cold beverages. It was demonstrated that iced water ingestion was followed, in this patient, by transient episodes of supraventricular tachyarrhythmias. The reproducible induction of acute, transient rhythm disturbance can possibly be explained by the temperature changes of either the pericardium or the left atrial wall, which have been experimentally shown to follow iced water swallowing. Whether this is a direct cause-to-effect phenomenon or one involving a neural mechanism cannot be currently inferred.
Explore the source record for details and available documents.
Two groups of patients with anatomically proved acute myocardial infarction were compared in order to study specificity and sensitivity of the ECG criteria previously described in clinical and experimental right ventricular infarction ( RVI ). Group 1 included 21 patients with left inferior infarction and with a variable degree of right ventricular involvement; group 2 included nine patients with myocardial infarction confined to the left inferior wall. In both groups the presence of ST elevation (at least 0.05 mV) and the morphology of the QRS complex in V4R , V3R, and V1 were assessed in ECGs performed at the time of admission. Also, in order to evaluate the morphology of the ST segment and QRS complex in right precordial leads in normal subjects, an ECG with 12 standard and four right precordial leads ( V6R to V3R) was performed in 82 subjects (group 3) without clinical and ECG evidence of heart disease. Our data reveal that in normal subjects an rS pattern is always present in V3R and frequently (91%) in V4R . On the contrary, the presence of QS or QR complexes in both V4R and V3R are specific markers of right ventricular necrosis (specificity 100%; sensitivity 78%). The presence of injury and necrosis waves in V4R or V4R to V3R during inferior infarction is a useful diagnostic criterion in that it insures a highly specific diagnosis of acute RVI in the great majority (76 and 71%, respectively) of the cases with autopsy evidence of right ventricular involvement.
Explore the source record for details and available documents.
In order to determine the status of cardiovascular health knowledge, a standardized questionnaire was administered to 325 students (currently) in their last year, in 18 high schools of Trieste. The schools were divided into 3 groups according to their teaching programmes: technical schools (Group A), teacher-training colleges (Group B) and junior high schools (Group C). The adopted questionnaire was that developed by the cardiovascular centre of the University of Iowa, slightly modified by the authors, but keeping the "multiple choice" pattern. The questions were focused on the three major areas of anatomy, physiology and pathology. All the students answered the questionnaire although none with 100% accuracy. The highest performance (95% of correct answers) was given in the field of the physiology of the heart of effort, the lowest one concerned the position of the heart in the chest (20%). Fifty-seven per cent of the students refrained from answering the question on myocardial ischaemia. The total score (based on the number of correct answers, incorrect ones and the number of blanks) revealed a significantly different level of cardiovascular health knowledge between the various school groups: group C (64.13 +/- 7.55) performed better than group A (67.15 +/- 9.45, P less than 0.001), which in turn was more successful than group B (71.6 +/- 10.0, P less than 0.001). In comparison to the group of 325 students, the score obtained by a sample group of hospital nursing students, showed a significantly higher level of health knowledge (46.1 +/- 1.56, P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
A feasibility study of health education was undertaken among the pupils of a primary school in order to: 1) investigate the level of participation of children and teachers to the program; 2) test the efficacy of the program itself; 3) determine whether the children can modify family's behavioral patterns of the family components. Seventy-two children, belonging to different socio-economic classes, were studied. Children were given a questionnaire at the beginning and the end of the programme course, which was held by previously trained teachers. The participation of children and teachers to the program was very satisfactory. On the contrary very low involvement of the parents was achieved. This experience emphasizes the difficulties that arise when interventions to modify adult people's life style are attempted. On the contrary, a standardized education program, to last a whole school year, could be a feasible useful and costless type of intervention not only for the primary prevention of coronary artery disease, but for any program of extensive health care.
To verify the level of participation of children and teachers in an educational program, the reliability of the program itself and to determine whether children can modify family's behavioral patterns, a feasibility study was undertaken among the pupils of a primary school. Seventy-two children, belonging to different socio-economic classes, were studied. Children were given a questionnaire before and after the course, which was held by previously trained teachers. Very good participation of children and teachers in the program was observed. On the contrary very low involvement of the parents was achieved. This experience emphasizes the difficulties arising when actions to modify adult's life styles are attempted. On the contrary, a standardized education program, lasting for a whole school year, could be a feasible, useful and not too costly program not only for the primary prevention of coronary artery disease, but for any program of extensive health care.
Pharmacologic myocardial reperfusion is a new strategy in the treatment of acute myocardial infarction, but its widespread use has raised several problems which are still unsolved. The time limit from the onset of ischemic pain until the beginning of thrombolysis is undefined yet. Experimental and clinical observations set this time within three hours. A reopened vessel is still at risk for reocclusion and anticoagulants are not always effective in the prevention of this. It is likely therefore that pharmacologic thrombolysis is only one step in the process of myocardial salvage and that other techniques like transluminal coronary angioplasty and/or coronary bypass surgery, should follow shortly. Intracoronary thrombolysis does not carry an increased risk for acute myocardial infarction patients. However haemorrhagic complications are expected to occur in less than 6% of cases during their hospital stay. To evaluate the extent of myocardial salvage quantitative ventriculography and intracoronary thallium 201 scintigraphy represent the most reliable techniques. Only the results of the continuing randomized trials will clarify the efficacy of this new way of therapy for morbidity, mortality and myocardial salvage.
This report describes a 25-year-old man who died due to extensive cystic medionecrosis of the aortic wall complicated by both an acute and an ancient dissection. The very unusual finding of an intravascular papillary endothelial hyperplasia, also known as Masson's pseudoangiosarcoma, in the dissected wall is reported given its resemblance to a hemangiosarcoma.