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Biomedical subjects

C Paquet

Publications and source records attributed to C Paquet.

7 recordsLinked to original sources
PubMed1976

Critical evaluation of the logit-log plot for the radio assay of vitamin B12.

The dose-response calculation for radio assay of vitamin B12 is carried out using a straight line and a third degree curve to fit the experimentally obtained calibration points. It is shown that high dispersion of the calibration points with respect to the regression line can lead to errors in the calculation of the response. The calculation of the mean dispersion sx with respect to the regression line turns out to be a good criterion for checking the accuracy of the results.

Evaluation Studies as Topic↗
PubMed1965

[Thyroid suppression test].

A test in which thyroid function is suppressed was evaluated in regard to its ability to confirm the diagnosis of hyperthyroidism in borderline cases. An effort was made to establish a standard technique by determining the required duration of administration of tri-iodothyronine. Twenty-seven normal controls received tri-iodothyronine (T(3)) for a 10-day period, and 24-hour I(131) uptake was determined after three, six and 10 days. Twenty-two normal controls were similarly studied after four days of T(3) treatment. Twenty-one patients with an elevated I(131) uptake without goitre or toxicity, 10 with non-toxic goitre and 11 with toxic goitre were also studied. The T(3) suppression test was found to be particularly useful in distinguishing toxic goitre from euthyroid patients with an elevated I(131) uptake. Four days of suppression were found to be sufficient for purposes of evaluation in a large majority of cases.

Adult↗
PubMedDate not supplied

[Flunitrazepam and memory (author's transl)].

This work is based on the observation of memory troubles before sleep in patients with sleep problems treated with flunitrazepam. Eight subjects are tested in two sessions, flunitrazepam and placebo, in double blind, with memory tests given the evening after medication and controlled the next morning. One additional test is controlling vigilance. The results show that memory is significantly disturbed by flunitrazepam, both for direct and delayed memory, the next day. On the contrary, recognition is not altered, neither vigilance.

Adult↗