PubMed Health⌕ Search

Biomedical subjects

C Paschalis

Publications and source records attributed to C Paschalis.

6 recordsLinked to original sources
PubMed1991

The psychopathology of suicide in the north western Peloponnesus.

A postmortem inquiry of 105 legal documents concerning suicide deaths obtained from the Office of the District Attorney covering the province of Achaia was studied for the 15-year period 1970-1984. The suicides were classified into two groups; group A consisting of 63 suicides (with a history of psychiatric illness) and group B consisting of 42 suicides (with no history of psychiatric disturbance). The findings suggest that people with a history of psychiatric illness committing suicide are disorganized in their personal and social life, with frequent previous suicidal attempts. Whereas, the nonpsychiatrically diagnosed group seemed to commit suicide under outside pressures which dislocated their lives progressively or abruptly. The differences between the two suicide groups are discussed and compared with similar studies regarding suicidal behavior.

Adolescent↗
PubMed1979

Urinary dicarboxylic acids in patients receiving lithium or rubidium salts.

Lithium salts administered in therapeutic doses to four subjects who were kept on controlled diets increased up to fivefold the urinary output of some dicarboxylic acids. Some of the acids affected are intermediates in the tricarboxylic acid cycle, others are chemically similar but not directly related in metabolic terms. This is probably a direct effect on renal transport. Rubidium salts increased urinary 2-oxoglutarate output and blood 2-oxoglutarate levels, probably by some action on intermediary metabolism.

Bipolar Disorder↗
PubMed1978

Nerve fibre refractory period in patients treated with rubidium and lithium.

Nerve fibre refractory period distributions have been measured on the median nerves of six manic-depressive patients controlled with lithium carbonate, three chronic patients (two manic-depressives and one catatonic schizophrenic) controlled with rubidium chloride, and eight normal volunteers. Rubidium prolonged the refractory periods of all nerve fibres while lithium increased only the longer refractory periods.

Adult↗
PubMed1978

Effects of rubidium chloride on the course of manic-depressive illness.

Clinical studies of the effects of rubidium ions on the course of manic-depressive illness are reported. It seems that rubidium tends to increase the length of manic phases and possibly reduces the extremes of mood. Rubidium did not seem to produce any severe side effects in the dose administered, but it has a long biological half-life and caution is still required. Some details of the CSF, RBC, saliva and plasma and urine kinetics are also reported.

Adult↗
PubMed1976

Lithium and the antidiuretic hormone.

The effect of lithium on the urine concentrating response to antidiuretic hormone (ADH) and the excretion of ADH has been studied in rats and man. The maximum urine osmolarity following 18 h dehydration and Pitressin (5 u) was decreased in three out of four patients during lithium treatment compared to their response to the same test in the absence of lithium. In a fifth patient, tested only during lithium treatment, the urine remained hypotonic to plasma throughout this test. Lithium increased the excretion of ADH in non-polyuric patients from 9-22 mu/24 h in the absence of lithium to 36-202 mu/24 - during lithium treatment. In four patients with lithium-induced polyuria, a diuretic acting on the distal tubules, clorexolone, reduced the polyuria. Lithium increased urine volume and the excretion of ADH in four rats receiving lithium in their diet. The response to exogenous ADH was decreased during lithium administration.

Animals↗