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Biomedical subjects

C Peluffo

Publications and source records attributed to C Peluffo.

5 recordsLinked to original sources
PubMed1975

The incidence of premature contractions in coronary patients during the sleep-awake cycle.

Mean heart rates and their variability indices during REM sleep and the frequency of cardiac arrhythmias during the sleep-awake cycle were determined in a group of coronary patients with disturbances of cardiac rhythm. In some patients there was a temporal relationship of atrial and ventricular premature contractions with slow-wave sleep, REM sleep or wakefulness. However, when they were considered as a group, no significant correlation could be observed. Furthermore, the sinus arrhythmia characteristic of REM sleep was not found to be exaggerated in those patients.

Adult↗
PubMedDate not supplied

Active infective endocarditis in infants and childhood: ten-year review of surgical therapy.

We review our 10-year (June 1987-June 1997) experience in 26 children requiring early surgery due to active infective endocarditis (AIE) refractory to medical therapy. Mean age at operation was 5.0 (SD 3.5) years. Nineteen patients (73%) had predisposing factors: congenital heart disease (CHD) was the most common (10/19, 53%); endocavitary foreign materials (6/19); and previous cardiac surgery (3/19). Vegetations or valve dysfunction was detected by transthoracic echocardiography in all cases but one. Valvular location (17/26, 65%) was the most common; others locations included cardiac chambers (8/26) and intravascular thoracic aorta (1/26). Bacterial isolation was achieved in 19 patients (73%): Staphylococcus (10 patients); Streptococcus (6 patients); and Candida albicans (3 patients). The indication for surgery was progressive or persistent cardiac failure (2 patients) or infection (9 patients), or a combination of these (7 patients), despite adequate medical therapy; major embolic accident with a mobile vegetation (4 patients), recurrent pulmonary embolism with a mobile vegetation (3 patients), and mobile vegetation (> 10 mm) in left cardiac chambers (1 patient). All the patients required surgery before 6 weeks of antibiotic therapy had been completed. The hospital mortality was 19% (5/26, 70% confidential limits[CL]: 2-35%). Deaths were due to infective causes in all cases but one. No late deaths occurred in 18 patients followed up for a mean of 4.2 years (SD 2.4). Three patients needed four reoperations. We conclude that improvement in the treatment of children with AIE can be obtained with an early and accurate diagnosis, an adequate antibiotic treatment, and a more aggressive surgical approach.

Child↗
PubMedDate not supplied

Human intramyocardial oxygen detected through chronic polarographic electrodes.

The intramyocardial PO2 was studied in 7 patients after cardiac surgery, by means of a long-term electrode implanted subepicardically in the free wall of the left or the right ventricle, utilizing the polarographic method. Inhalation of 100% O2 or 5% CO2 +95% O2 provoked maximal increases in the myocardial PO2. In most cases intense exercise, and the Valsalva manoeuvre caused a decrease in the PO2. Intravenous propranolol slightly increased the PO2 in one case. Other drugs used in coronary patients caused inconstant effects. Sleeping decreased the heart PO2 in one case. This technique appears to be a useful tool for studying the human intramyocardial PO2 during a period of several weeks.

Adolescent↗