Biomedical subjects

C Pernegger

Publications and source records attributed to C Pernegger.

6 recordsLinked to original sources

PubMed1996

Intraperitoneal cholelithiasis after laparoscopic cholecystectomy--behavior of 'lost' concrements and their role in abscess formation.

UNLABELLED: In two experimental studies we sought preliminary information about the behavior of concrements lost in the peritoneal cavity during laparoscopic cholecystectomy. MATERIALS AND METHODS: In study 1, human gallstones were analyzed using X-ray diffraction, classified in three groups and examined with an ultramicroscope; then they were implanted in the peritoneal cavity of rats. After 8 weeks or 6 months, the animals were sacrificed and the concrements analyzed again as before. The tissues surrounding the calculi were also examined histologically. In study 2, human gallstones were examined with regard to bacterial contamination on the surface or in the middle of the calculi. The cholesterol content was analyzed, and the stones were divided into three groups and implantated in the rats as in the first study. After 8 weeks, the animals were sacrificed and areas with identifiable tissue reactions were examined histologically and microbiologically. RESULTS: The concrements lost their crystalline formation without any relation to their former cholesterol content, as shown by X-ray diffraction as well as ultramicroscopy. Mineralogically, these changes are a certain sign of structural dissolution. Cholesterol stones only caused abscess formations in association with gram-negative bowel germs. Sterile pigment concrements often led to a mesenchymal reaction such as granulomas. Contaminated pigment stones also resulted in extensive abscess formations.

Abscess↗

PubMed1994

Systemic phlebitis of visceral veins with intramural giant cell granulomas--a new entity?

We report a case of granulomatous giant cell poly-phlebitis of the mesenteric veins in a 38-year-old man, resulting in a segmental infarction of the ileum. Multiple epithelioid granulomas with giant cells of the Langhans type were situated in media/adventitia of small and middle-sized mesenteric veins with subsequent thrombotic occlusions. No involvement of arterial vessels could be detected. The etiology of the disease remains unknown. Any known type of vasculitis could be excluded. An immunology-related vasculopathy is assumed, but could not be definitely proved. This is the first case of a granulomatous giant cell poly-phlebitis of visceral veins reported in the world literature.

Adult↗

PubMed1994

[Laparoscopy-assisted reoperation after sigmoid resection and Hartman rectal occlusion].

The anastomosis between the descending colon an the rectal stump after sigma-resection and blind closure of the rectum according to Hartmann could be performed as well via an open laparotomy approach as via a laparoscopic procedure. By means of a first group of five laparoscopically reoperated patients the authors are demonstrating the good practicability of their laparoscopic method. Extended adhesions in the pelvic area could be detached in all cases. The advantages of this laparoscopic operation are obvious and in the authors opinion laparoscopic assisted reconnection between colon and rectal stump seems to be a serious alternative to open surgery by laparotomy.

Adult↗

PubMed1993

Primary granulomatous giant cell polyphlebitis of visceral veins.

A case of granulomatous giant cell phlebitis occurred in the mesenteric veins of a 38-year-old man, resulting in segmental infarction of the ileum. Multiple epithelioid granulomas with giant cells of the Langhans type were situated in media/adventitia of small and middle-sized mesenteric veins with subsequent thrombotic venous occlusions. No involvement of arterial vessels could be detected. The aetiology of the disease remains unknown. Known types of vasculitis were excluded. It was assumed that this is an example of in immunological vasculopathy but this could not be proved.

Adult↗

PubMed1992

[The cystic duct stump after laparoscopic cholecystectomy].

The aim of this study was to evaluate the length of cystic-duct stumps after laparoscopic cholecystectomy. 113 patients underwent intravenous cholangiography 2 to 3 months postoperatively, whereby a cystic-duct remnant of up to 1 cm was found in 34.5% (n = 39) and between 1 and 2 cm in 36.3% (n = 41). In 24.8% (n = 28) a stump measuring 2 to 3 cm was registered and in 4.4% (n = 5) the cystic-duct remnant was more than 3 cm. Possible consequences with regard to the development of the postcholecystectomy syndrome are discussed. In our experience laparoscopic cholangiography seems to be a useful procedure to detect cysticolithiasis and as preliminary measure to undertaking the correct therapeutic steps. Adherence of this strategy might avoid possible later complications by elimination of their principal cause.

Cholangiography↗

PubMed1992

[Laparoscopic cholecystectomy--current status].

Laparoscopic cholecystectomy (LCHE) is a safe and effective way to treat gall stones. The procedure was carried out for the first time in France in 1987 and since then it has spread rapidly all over the world, in view of the excellent results achieved. The major benefits are the low morbidity, the very short hospitalization, the early return to daily life and work and its excellent cosmetic results. LCHE is indicated in symptomatic non-complicated gall-bladder disease. The operative technique is standardized, the complication rate is low. Compared with other treatments such as litholysis, extracorporeal shock wave therapy and standard cholecystectomy it is a superior, definitive alternative, which is prognosed to become the therapy of choice in gallbladder disease.

Adolescent↗