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Biomedical subjects

C Petermann

Publications and source records attributed to C Petermann.

18 recordsLinked to original sources
PubMed1999

Relapsing pneumonia due to a migrating intrathoracic foreign body in a World War II veteran shot 53 years ago.

In the great majority of cases of long-standing intrathoracic foreign bodies, patients are asymptomatic. However, symptoms may occur years later from the migration of the foreign body. We report on a 70-year-old patient who developed relapsing pneumonia due to obstruction of a bronchial branch of the left apical group by a migrating infantry bullet impacting 53 years ago. This was not diagnosed until the second attack of pneumonia in 1998. The bullet remains were removed bronchoscopically and the pneumonia resolved completely without further complications.

Aged↗
PubMed1998

[Long-term experiences with mechanical patient-controlled analgesia pumps for therapy of postoperative pain in general surgery].

The efficiency and safety of patient-controlled analgesia (PCA) in the treatment of postoperative pain is well documented. An alternative to electrical systems is the disposable pump, which is cost effective. The aim of this study was to prove the efficiency and safety of PCA disposable pumps. Eighty patients (45 men, 35 women, mean age 50 +/- 16 years) were included and received single-use PCA pumps (Vygon Medical Products, Aachen, Germany) for postoperative pain control. A sufficient reduction in pain levels, measured by the Verbal Rating scale (VRS), was achieved in nearly all patients. For the first application, a single bolus of 7.0 +/- 2 mg piritramide (Dipidolor) was needed, the mean of treatment time was 56 +/- 31 h. We had two dropouts because of non-compliance, two patients felt dizzy, and one patient felt nauseous. Further side-effects were observed during treatment. Our study led us concluded that PCA therapy with mechanical, disposable pumps is a safe and efficient treatment for postoperative pain. Such a concept can be introduced without an "Acute Pain Service" if the staff are well trained.

Adolescent↗
PubMed1998

[Inflammatory pseudotumor of the spleen as an incidental asymptomatic finding in a 44-year-old patient].

In the era of routinely used ultrasound techniques intrasplenic tumors are diagnosed more frequently. Usually these findings are not combined with specific symptoms. However, large cysts can lead to malfunctions of nearly located organs by displacing. Etiopathogenetic findings in our region are mainly non parasitic, epithelial and traumatic cysts or tumors of the spleen. We describe a large splenic mass of a 44 years old female patient. Pathological dignity remained unclear after using sonographic, radiological and clinical techniques. After uncomplicated total splenectomy the histopathological diagnosis revealed a benign, pseudoinflammatory tumor of the spleen. Inflammatory pseudotumors are a benign response to an unknown cause. It must be a main objective of preoperative diagnostics to distinguish them from malignant processes.

Adult↗
PubMed1995

[Diagnostic and therapeutic problems of acute lower gastrointestinal hemorrhage].

In a four year period (1990-93) 75 patients were treated in our hospital for acute lower gastrointestinal bleeding. In the course of diagnostic procedures an upper gastrointestinal bleeding was excluded routinely and further 126 endoscopic measures were performed. All patients underwent rectoscopy and additional partial or total coloscopy. In addition to that, 16 scintigrams and 7 angiograms were taken. The validity of the endoscopic measures was 0.73, scintigraphy and angiography were less valid with 0.53 and 0.34. Therefore endoscopic diagnostic procedures are of more value. 32 of these 75 patients underwent operative treatment. Recurrent bleeding after operative treatment was seen in 6.25%. Overall mortality was 5.33%. Because prognosis of a recurrent bleeding after operative treatment is poor, primary subtotal colectomy is indicated when the source of bleeding can not be localized.

Aged↗
PubMed1990

[Individual prognosis in gastroduodenal ulcer hemorrhage: practical application].

Using modern methods of medical decision making (regression analysis) one can determine risk factors for rebleeding in peptic ulcer disease. Prediction of rebleeding for the individual patient is possible. Under regard of five effective risk factors and using adequate statistical methods, sensitivity and specificity reach about 80%.

Decision Support Techniques↗
PubMed1985

[Standardized ulcer surgery. Results of 10 years' experience].

In ten years a total of 1207 operations for gastroduodenal ulcer were performed, using a standardizing treatment scheme. The number of operations has markedly decreased since 1978, probably due to the introduction of H2-receptor blockers in the treatment of peptic ulcers. The results of operations suggest elective surgical treatment for ulcer patients at risk of complications. This is the only way of decreasing the adverse effect of emergency operations on the total surgical mortality of ulcer patients.

Adolescent↗
PubMed1983

[Drug therapy of peritonitis. 6-year experience with the chemotherapeutic agent and anti-endotoxin taurolin].

Since 1976 Taurolin is applied in clinical trials in several European states. The results being submitted show a very good activity of this substance against bacteria and endotoxin. Evaluating all clinical and experimental studies in our opinion the use of antibiotics postoperatively together with Taurolin seems to be an effective treatment of peritonitis. In our hospital taurolin has become an important part of the surgical management of severe forms of peritonitis. A development of resistant bacteria is not known up to now.

Anti-Bacterial Agents↗
PubMed1981

Synthesis of gamma-methyl-L-leucine (neopentylglycine, Neo) and derivatives suitable for peptide synthesis.

The modified Strecker synthesis of Patel & Worsley was combined with an enzymatic deamidation in the final step, to produce the title compound. The amino acid is a member of the family of the "fat" amino-acids with high lipophilicity and space-filling properties, as estimated by its Hansch hydrophobicity constant pi and its Charton steric parameter v. It can be used for qualitative and quantitative studies of structure-activity relationships in biologically active peptides. Three of its derivatives suitable for peptide synthesis are also described.

Leucine↗
PubMed1980

[Thyroid hormone levels after surgical stress reaction (author's transl)].

In a larger collective of surgical patients the behaviour of the individual thyroid parameters (T4, T3, rT3, TBG and thyroxine-binding capacity) were studied before, during and after operation and set in relation to each other. There are significant shifts in T4 metabolism towards the formation of rT3. In spite of its greatly reduced metabolic activity compared with T3, an important regulatory effect is attributed to rT3, in thyroid metabolism in stress situations.

Adult↗
PubMed1980

[Problems after surgery of acute abdomen].

Many problems may persist after operation of an acute abdomen. Most important are peritonitis, hemorrhage, vascular occlusion and reduced general condition. Pathophysiology, clinical symptoms and therapeutic principles are discussed.

Abdomen, Acute↗