PubMed HealthSearch

Biomedical subjects

C Philips

Publications and source records attributed to C Philips.

13 recordsLinked to original sources

Obesity can be treated by suction lipoplasty when combined with other procedures.

The development of serial suction lipoplasty enables us to remove substantial amounts of subcutaneous fat safely and dependably on an outpatient basis, and free our patients of the worry of exogenous blood transfusion. Many practitioners and researchers do not advocate suction for the treatment of obesity, but rather regard it as a means of treating localized small deposits of fat or "figure faults." The reason for their caution is that the amounts of fat to be removed from the obese patient would require extensive hospitalization, transfusion, and increased risk of complications. Liposuction, when performed as a series, can make the treatment of obesity as safe as the treatment of smaller figure faults. We now use serial suction as an adjunct to other surgical and dietary methods for the control of obesity.

Adult

Temporal spacing of pattern alternation and human visual response.

The electroretinogram and the visual evoked potential were recorded in response to checkerboard stimuli presented in phase alternation. The times in which the pattern was in its two positions were changed within a fixed total cycle time of two seconds. Both the amplitude of the electroretinogram and the evoked potential were affected by the length of the time interval between alternations, but in opposite directions. An electroretinogram that closely followed a preceding response was reduced in size while an evoked potential was larger. The results indicate that there is an interaction between adjacent pattern areas at the retinal level.

Electroretinography

Radiation measurement with a solid-state-matrix camera.

A solid-state-matrix camera containing 32 X 32 photodiode array served as the output device on an image intensifier tube. The resulting images had poor spatial resolution but permitted precise measurement of x-ray intensity. Transmission differences of 1% were detectable.

Fluoroscopy

Interpositional arthroplasty for rheumatoid carpometacarpal joint disease.

Over the past 3 years the Swanson great toe prosthesis was used in an interpositional arthroplasty at the carpometacarpal joint in 21 thumbs of 19 patients with rheumatoid arthritis and three thumbs of two patients with lumpus arthritis. In selected patients with advanced disease, this prosthesis has the advantage of allowing for correction of deformity while preserving carpal stock which may be important if a surgical procedure is required at the wrist. Stable capsular closure does not require reinforcement by adjacent tendon. Twenty-two thumbs of 19 patients were improved, although in three the prosthesis was malpositioned. Two patients required reoperation and removal of the prosthesis: one for infection, and one for failure to correct deformity. Overall functional results often were affected by the status of disease in other joints, but in general were acceptable.

Adult

Studies of skeletal tracer kinetics. I. Digital-computer solution of a five-compartment model of [18F] fluoride kinetics in humans.

We have developed a new model of short-term fluoride kinetics in humans and have solved the model on a digital computer using the SAAM-25 program. The solution accords well with available data. About 60% of intravenously administered [18F] fluoride is taken up by bone. Evaluation of the rate constants of tracer egress from blood indicates that about 17% of the cardiac output is distributed to the skeleton. When the model was perturbed to simulate changes in systemic or skeletal blood flow, we found that the system behaves in a nonlinear manner; even a five-fold increase in systemic or skeletal blood flow did not appreciably increase the amount of fluoride taken up by bone 1--2 hr later, the time when scans are usually made. A simulated increase in bone extraction rate, however, had a marked effect on bone-fluoride uptake. These findings suggest an important homeostatic role for bone in the regulation of blood calcium concentration and have considerable bearing on the interpretation of bone scans.

Bone and Bones

Combined wrist arthrodesis and metacarpophalangeal joint arthroplasty in rheumatoid arthritis.

This paper describes a surgical procedure which combines wrist arthrodesis and metacarpophalangeal joint arthroplasty into one operation. Its basic indication is the severely crippled rheumatoid patient who is faced with multiple reconstructive surgical procedures. In addition to the combined wrist fusion and metacarpophalangeal joint arthroplasty, other surgical procedures can sometimes be performed into same hand, thereby completing the entire reconstruction in one operation. Of the 19 patients who have undergone the combined procedure, only one failed to obtain a solid clinical arthrodesis. There were no infections, skin sluffs or other complications. Combining the two procedures did not jeopardize either wrist fusion or metacarpophalangeal joint arthroplasty. Specific contraindications for the procedure are fixed wrist flexion contracture or a complete dislocation requiring extensive exposure in order to align or reduce the radiocarpal joint.

Adult