Non-O1 Vibrio cholerae gastroenteritis and bacteraemia.
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Biomedical subjects
Publications and source records attributed to C Piersimoni.
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A new test combination for presumptive phenospecies identification of mesophilic aeromonads by testing for suicidal activity in conjunction with esculin hydrolysis and gas production from glucose was evaluated. Of 40 clinical isolates of Aeromonas tested statically at 30 degrees C, seven were identified as Aeromonas hydrophilia (non-suicidal, aerogenic, esculin positive), eight as Aeromonas sobria (suicide variable, mostly aerogenic, esculin negative), and 25 as Aeromonas caviae (suicidal, anaerogenic, esculin positive). The results corresponded exactly to those obtained with the conventional biochemical tests. The test combination was rapid and simple to perform.
16 patients with Kaposi's Sarcoma were examined with in vitro tests for cellular immunity and with determination of antibody titres to Cytomegalovirus. It was stated that the Cytomegalovirus antibodies were related with new viral infections favoured by the immunosuppression.
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9 patients with Kaposi's sarcoma, not treated with immunosuppressant drugs, were studied. In the Kaposi's disseminated form an impaired function of T mediated immunity (Leukocytes migration inhibition for PHA and PPD and skin test for DNCB) was found. The number of T lymphocytes (E rosettes) was normal. In the Kaposi's initial form with multiple dermal plaques and nodules, these alterations of cellular immunity were absent. In 4 patients elevated titles of Cytomegalovirus antibodies were found. The occurrence of an impairment of cellular immunity only in the serious and disseminated Kaposi's form is emphasized by the Authors.
A series of N-(2-hydroxyethyl)-1,2-benzisothiazol-3(2H)-one and -thione carbamic esters have been synthesised and tested against Mycobacterium avium strains. The MIC values determined by the radiometric broth dilution method were between 2 and 8 micrograms/mliters for the benzisothiazolthione derivatives and between 16 and 32 micrograms/mliters or higher for the corresponding benzisothiazolone derivatives.
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