PubMed Health⌕ Search

Biomedical subjects

C Povysil

Publications and source records attributed to C Povysil.

5 recordsLinked to original sources
PubMed1997

Causes of death in geriatric patients: a cross-cultural study.

BACKGROUND: The elderly are living longer and causes of death are shifting. At the same time, autopsy rate is at, or near, its lowest in history, compounded by an even lower interest in geriatric autopsies. Thus, the prevalent cause of death in this age group remains poorly studied. METHODS: In a retrospective study, the autopsy protocols of 440 70-year-old or older patients from the Houston Veterans Affairs Hospital and 321 80-year-old or older patients from the II*Institute of Pathology in Prague (Czech Republic) were reviewed in order to establish a correct cause of death. The autopsy diagnosis was correlated with the prosectors' description of pathological findings in the protocol. In questionable cases or discrepancies, the patient's clinical chart and/or the histological autopsy slides were also reviewed. RESULTS: The distribution of death by infections and cardiac disorders each accounted for one-third of all deaths. Congestive heart failure prevailed in the over 80-year-olds, and myocardial infarcts prevailed in the younger patients. The number of deaths due to malignancy dropped from 25% in those 70-79 years old to about 10% in the elder patients. Central nervous system disorders were frequent as an underlying disease, but were not common as a cause of death. The findings were similar in both series, thus supporting their accuracy. CONCLUSION: Our findings bring into question the accuracy of reported causes of death in the elderly. With increasing age, differences appear in the levels of mortality and morbidity for various disease categories. This study underlines the need for more baseline data for older people which can be obtained only by more and well-performed autopsies.

Aged↗
PubMed1986

[Ewing's sarcoma. New clinico-pathological aspects].

Ewing's sarcoma is a rare, but highly malignant bone tumor. During the years 1966-1983 we diagnosed and treated this tumor in 84 patients. Diagnosis of the tumor in an early stage is a prerequisite for successful therapy. Clinical and radiological findings contribute to the diagnosis, but histologic confirmation is indispensible. In addition to histomorphology we regard electron microscopy and the demonstration of glycogen as essential for the final diagnosis. The differential diagnosis includes haematogeneous osteomyelitis, malignant lymphoma, metastases from neuroblastomas, rhabdomyosarcoma and some benign bone tumors. New observations concerning the histogenesis of Ewing's sarcoma are discussed. The introduction of chemotherapy as part of a multimodality approach to treatment has substantially improved the prognosis in comparison to the previous results with surgery and radiation therapy. The role of surgery and radiation independently and in combination is discussed. We propose an approach to treatment based on our experience which involves surgical removal of the primary tumor after preoperative chemotherapy. The overall survival rate among our 84 patients was 40%. Among those who were diagnosed early and treated according to the recommended protocol 54% are alive.

Adolescent↗
PubMedDate not supplied

Clinical study of the effect of hydroxyapatite on osteointegration by total hip replacement.

From 5.1989 to 12.1992, the Walter-Motorlet cementless hip endoprosthesis provided with "Arbond" hydroxyapatite coating was clinically tested. This femoral component was applied to 34 patients, among those 26 women and 8 men having the average age of 42 years (range 24-82 years). We compared the results with a control group of patients constituted of 20 men and 49 women on average 48.3 years of age, in which the same type of endoprosthesis was used, but without hydroxyapatite coating. Both groups were evaluated by the same surgeons according to the usual international standards (ALLOPRO CHART). The substantially higher quality of the osteointegration of the hydroxypatite implants especially where primary osseous fixation is not quite stable and thus not perfect is undoubtedly evident from this study.

Adult↗