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Biomedical subjects

C Price

Publications and source records attributed to C Price.

At least 163 records · Page 9Linked to original sources
PubMed1989

Emulsion clearing characteristics in the processing of dental radiographic films.

Recent problems in the fixation of dental X-ray films during processing have led to a study of the clearing of dental emulsions. A method has been devised to compare the behaviour of different emulsions and fixing chemistry under varying conditions of time and temperature. The ease with which emulsions clear has been shown to relate to the fixer chemistry, temperature and time of fixation and, for D-speed films, to the speed of the emulsion. The density of the residual silver halide is approximately inversely proportional to the time and temperature for the ranges explored. E-speed emulsion was less affected than D-speed by fixer chemistry, time and temperature. Fixation is relatively less influenced by temperature changes than development. A suspected relationship between clearing ability and emulsion thickness has not been demonstrated reliably in this investigation. The evaluation of these variables is of relevance to those concerned with the manufacture of films, processors, and processing chemistry as well as to those who process X-ray films.

Radiography, Dental↗
PubMed1988

A community-based support group for HIV positive i.v. drug abusers: the HERO program.

The I.V. drug abuser who has a history of non-compliance is perhaps the most difficult to reach among those at risk for contracting AIDS. This article details one approach being attempted at HERO, that of a community-based support group run by an indeginous worker where the emphasis is on support, education, and outreach to others. HERO's program is also highlighted.

Acquired Immunodeficiency Syndrome↗
PubMed1988

Thrombolytic therapy in acute arterial thrombosis.

The courses of 17 patients who underwent 20 separate attempts at thrombolysis for acute arterial thrombosis are reviewed to clarify the safety and efficacy of this therapy. Seventeen of 20 thrombolyses were angiographically successful. Patients who had correctable lesions identified and reconstructive procedures performed tended to do better than those who did not, and patients who had successful thrombolysis tended to have fewer and less radical amputations. Complications can be reduced by careful, close monitoring of patients undergoing therapy.

Acute Disease↗
PubMed1988

Q fever following bone marrow transplantation.

We describe a patient who developed an acute febrile illness 85 days after receiving an allogeneic bone marrow transplant for acute myeloid leukaemia. Serological investigation indicated the cause to be Q fever. The patient was receiving concurrent immunosuppressive therapy for graft-versus-host disease (GVHD). Coxiella burnetii should be added to the list of organisms which may complicate bone marrow transplantation. This case also provides further evidence to support an association between immunocompromised conditions and the development of Q fever.

Adult↗
PubMed1987

EcoR124 and EcoR124/3: the first members of a new family of type I restriction and modification systems.

We have purified the EcoR124 and EcoR124/3 restriction enzymes and shown that they are type I enzymes by several criteria: subunit composition, DNA and S-adenosylmethionine-dependent ATPase activity, and site-specific DNA methylase activity. By immunochemical criteria these enzymes are related to each other but are unrelated to the two previously investigated families of type I restriction enzymes. They form therefore a new family which we call type IC. The arrangement of the structural genes coding for these enzymes and their transcriptional organisation have been determined. These are different from the common arrangement found for the other two families of type I enzymes.

Adenosine Triphosphatases↗
PubMed1987

Endorphins are related to pain perception in coronary artery disease.

Plasma beta-endorphin levels were measured by radioimmunoassay before and after exercise in 25 patients with coronary artery disease. Eighteen patients were men and 7 were women; age range was 36 to 75 years (mean 60). All patients had angina pectoris, a positive treadmill test response or positive exercise radionuclide findings. The mean preexercise plasma endorphin level was 4.9 +/- 3.0 pmol/liter (range 0.7 to 13.5). The mean postexercise plasma endorphin level of 6.6 +/- 4.6 mol/liter (range 0 to 19.5) was significantly higher (p less than 0.05). A significant positive correlation was seen between postexercise endorphin levels and time to onset of angina (r = 0.4, p = 0.03). There were negative correlations between postexercise endorphin levels and occurrence (r = -0.4, p = 0.04) and duration of angina (r = -0.4, p = 0.05). No association was found for maximal heart rate-blood pressure product, workload, time to ST-segment depression or stress ejection fraction. A positive correlation was found between rest left ventricular ejection fraction and postexercise endorphin levels (r = 0.5, p = 0.02). In conclusion, in patients with exercise-induced myocardial ischemia, plasma beta-endorphin levels are increased after exercise; postexercise endorphin levels are related to timing and occurrence (presence or absence) of angina; and endorphins may alter the perception of pain caused by myocardial ischemia.

Adult↗
PubMed1987

DNA recognition by a new family of type I restriction enzymes: a unique relationship between two different DNA specificities.

The DNA sequences recognized by the allelic type I restriction enzymes EcoR124 and EcoR124/3 were determined. EcoR124 recognizes 5'-GAA(N6)RTCG-3' and EcoR124/3 recognizes 5'-GAA(N7)RTCG-3'. These are typical of sequences recognized by type I recognition enzymes in that they consist of two specific domains separated by a non-specific spacer sequence. For these two enzymes, the specific sequences are identical but the length of the non-specific spacer is different. The specific domains of EcoR124/3 are thus 3.4 A further apart than those of EcoR124 and rotated with respect to each other through a further 36 degrees.

Base Sequence↗