[Apoplectiform processes in tumors of the central nervous system: pathogenetic, diagnostic and therapeutical problems (author's transl)].
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Biomedical subjects
Publications and source records attributed to C Probst.
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Parinaud's syndromes may occur in infra- and supratentorial space-occupying lesions, but very careful differential diagnosis must be made in those cases. Occurring peripheral signs are due to brain mass displacements caused by transtentorial brain herniae. The prognosis is relatively good if the space-occupying lesions may be entirely or at least sufficiently removed. Five corresponding cases are described and clinical, neuroradiological and surgical findings discussed.
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100 cases of Spitz-Holter shunts performed for hydrocephalus over a period of 3 years were analyzed; 17 of these were of posttraumatic origin and are discussed in regard to pathogenesis, clinical symptoms, diagnostic methods, and therapy. Half of these 17 had severe traffic accidents. The rapidity and degree of ventricular dilatation were positively correlated with the duration of unconsciousness. When the unconsciousness had lasted more than 10 days hydrocephalus was recognized early, and the shunt was performed on an average 2 months after the trauma. Two thirds of the patients improved after the shunt operation. Pathogenetically we believe the important factors in the acute stages are increased CSF pressure, disturbed CSF dynamics, brain swelling and vascular circulation disorder; in the chronic stages, parenchymous atrophy. The following 3 types of posttraumatic hydrocephalus were differentiated on the basis of the clinical features: --symmetrical communicating internal hydrocephalus with malresorption, especially after subarachnoid hemorrhage, --communicating internal hydrocephalus alone, or in combination with external hydrocephalus resulting from atrophy, --internal occlusive hydrocephalus after trauma. The following posttraumatic clinical features were found to be indications that hydrocephalus may be present: in the acute stages inadequately long symptom resolution considering the severity of the trauma, secondary changes for the worse, an apallic syndrome which does not improve; in late stages, the presence of an Adams-Hakim syndrome charaterized by dementia, a spastic gait and loss of sphincter control. The most successful diagnostic methods were found to be pneumencephalography with 24 and 48 h delayed exposures, cisternoscintigraphy and continuous intracranial pressure monitoring in combination with the spinal infusion test. The most important intracranial shunting procedures and the indications for shunting are discussed.
A case of dilatation of the right lateral ventricle due to membranous occlusion of the foramen of Monro is reported. A child aged two and a half years developed raised intracranial pressure together with disturbed consciousness, but other neurological defect, two months after after an attack of bilateral broncopneumonia. The preoperative diagnosis of occlusion of the right foramen of Monro by infiltrating tumour was made angiographically. At operation the obstruction was found to be due to a membrane. The septum lucidum was fenestrated and a ventriculoatrial shunt was inserted. After a year the shunt was removed. Twenty eight cases of unilateral hydrocephalus due to nontumorous occlusion of the foramen of Monro have been reviewed, and the aetiologies have been discussed. Clinical picture and diagnostic procedures are reviewed. The authors discuss surgical treatment, and lay stress on fenestration of the septum lucidum.
Displacements of the proximal humeral epiphysis at the epiphyseal plate result from extension injuries. The configuration of the epiphyseal plate and the thickness of the periosteum surrounding the epiphysis make slight to moderate displacements relatively stable injuries, which can be treated successfully with external support. In patients with more severe displacement, flexion, abduction, and slight external rotation of the distal fragment bring the metaphysis into alignment with the proximal fragment, correcting the anterior angulation. The thick periosteal sleeve attached to the physis through which the metaphysis tears out anteriorly has great potential for remodeling the persistant bowing that remains after healing of the fracture. Although shortening and residual angulation results from closed treatment are almost always good and open surgery is rarely indicated.
We report 2 cases of sphenoid ridge meningeomas with symptoms of a parkinsonian sydrome, one of them contralaterally, the second bilaterally. Both did not respond to specific antiparkinson treatment. The extrapyramidal symptoms disappeared in both cases promptly after removal of the tumor. In the first case they reappeared temporary in connection with a local wound-infection. The histological examination of the second case, which died on a pulmonary emboly, showed no alterations of the cerebrum in the sense of an idiopathic or postencephalitic M. Parkinson. The authors try to show possible corrlations by means of the relevant literature (total 75 cases). It is found, that extrapyramidal symptoms do not allow uniequivocal localising or specific conclusions referring the kind of tumor or lesion. Nevertheless the meningeomas preponderate, excluding the basal infiltrating tumors. Referring to the localisation, the frontal located meningeomas preponderate. The bilateral meningeomas all lead to bilateral extrapyramidal symptoms. Next it especially also the frontal meningeomas of convexity mostly cause bilateral extrapyramidal symptoms. In the majority of cases the diately after operation, the rest during weeks to months. Finally the authors discuss the possible pathophysiologic mechanism of origin according to the literature.
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