Oligodontia and transposition.
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Anodontia↗
Biomedical subjects
C R Culliton
Publications and source records attributed to C R Culliton.
Bacteriostatic effect of tetracycline in a temporary cement.
Temporary crowns with subgingival margins can result in gingival inflammation. This inflammation is the result of plaque accumulating at the restoration-tooth interface and a change in the nature of that plaque to one associated with periodontitis. It was postulated that tetracycline incorporated in a slightly soluble cement would be released in the sulcus and decrease the amount, and improve the quality, of the subgingival microflora. The unknown was whether tetracycline is inactivated by any of the components of the temporary cement Temp Bond. To determine this concern, disks of Temp Bond cement with and without varying concentrations of tetracycline were anaerobically incubated in cultures of Bacteroides gingivalis. Results showed that tetracycline incorporated in Temp Bond at 10% by weight is highly bacteriostatic while retaining typical working properties of the cement.
Bacteriological Techniques↗
A critical evaluation of the acute systemic toxicity test for dental alloys using histopathologic criteria.
The A.D.A. acute systemic test for type II, class 11 materials defines compliance on the basis of fewer than 50% mortality at 2 weeks. Histopathologic criteria were developed from pilot study data to evaluate the effects of these materials. In this double blind study, the frequency of histopathological changes in lung, liver, small intestine, and kidney were rated at 2 and 5 weeks, for six dental crown and bridge alloys ranging from 44% to 97% (Au, Pt, and Pd). Two positive 360 mg/kg and 1 g/kg of cadmium and two negative, a blank capsule and untreated control groups were used. There was significant difference (chi square test, X2 = 0.95) between the positive and negative controls at 2 and 5 weeks. The lung, liver, kidney showed the highest level of histopathological changes. Significant changes occurred in the four tissues for all alloys at two and five weeks. At five weeks, alloys with a lower noble metal content (44-62%, Au, Pd, and Pt) elicited significant chronic changes, while higher noble metal content (78-97%) showed healing and no significant difference from the negative controls. Applying histopathologic criteria and statistical parameters independent examiners can examine experimental animals and arrive at conclusive and reproducible results.
Animals↗