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Biomedical subjects

C R Daniel

Publications and source records attributed to C R Daniel.

10 recordsLinked to original sources

The spectrum of nail disease in patients with human immunodeficiency virus infection.

There are no known pathognomonic nail signs of human immunodeficiency virus (HIV) infection. However, several presentations should increase the index of suspicion. (1) Proximal white subungual onychomycosis or superficial white onychomycosis, especially of the fingernails, is present. Trichophyton rubrum appears to cause both most commonly in HIV-infected patients. Periungual dermatophyte involvement and involvement of all 10 fingernails is unusual in non-HIV-infected persons. (2) Candida is a primary pathogen of the nail bed and nail plate especially if many nails are involved. (3) A destructive, almost granulomatous-like psoriatic involvement of the nails is present. (4) Squamous cell carcinoma of the nail bed in a young adult. There are no clinical trails to confirm the efficacy of therapy mentioned in this article. The treatment suggestions are empirical and are the personal views of the authors.

Candidiasis, Cutaneous

Basic nail plate avulsion.

Correct partial or total nail plate avulsion may be performed in the physician's office. The author recommends certain preoperative, operative, and postoperative procedures that may help assure a more successful outcome.

Anesthesia, Local

Onycholysis: an overview.

Onycholysis is commonly seen in dermatological practice. To treat this disorder properly, it must be approached in an orderly manner. The cause must be ascertained and eliminated, if possible. General treatment principles and specific recommendations for diagnosis and therapy have been made.

Humans

Nail damage secondary to a hair spray.

Nail abnormalities secondary to contact with cosmetic preparations are well documented in the literature. This report documents a case of nail dystrophy apparently secondary to use of a hair spray.

Female

Vibrometry and uremic peripheral neuropathy.

The vibratory sensation threshold (VST) was measured with a vibrometer to assess the progression of neuropathy in patients with end-stage renal disease. Normal patients and patients receiving chronic hemodialysis were studied. We found that the longer the patients were dialyzed, the lower their VST (P less than 0.01). Regression equations were established to predict threshold values versus age of both groups, and VST versus months on dialysis in the patient population. Vibrometry was an important addition to the assessment of peripheral neuropathy in our dialysis patients. It offers low cost, little patient preparation, and requires little professional time for examination and interpretation.

Adolescent