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Biomedical subjects

C R Fitzgerald

Publications and source records attributed to C R Fitzgerald.

31 records · Page 2Linked to original sources
PubMed1978

Retinal receptive field-like properties and Stiles-Crawford effect in a patient with a traumatic choroidal rupture.

Simple psychophysical techniques were used in order to assess layer-by-layer retinal functions in a patient with sub-retinal fluid due to a choroidal rupture following ocular trauma. A substained-like and a transient-like function believed to reflect retinal receptive-field-like properties, and an indicator of retinal receptor orientation (the Stiles-Crawford effect) have been followed in time. Central visual acuity was also measured. Initially all measured functions provided anomalous responses in affected retinal areas. Of interest here is the nature and order of recovery of the measured response functions. Most notable was the rapid rate of recovery of receptor orientation and the slower rate of recovery of the transient-like function.

Adolescent↗
PubMed1976

Human psychophysical analysis of receptive field-like properties: V. Adaptation of stationary and moving windmill target characteristics to clinical populations.

This paper describes the application of several key parameters of a windmill-shaped target (used in determinations of the psychophysical transient-like function) to clinical populations as a diagnostic tool for static perimetry. A technique for independently analyzing sustained- (Westheimer function) and transient-like retinally-based psychophysical responses is outlined, and stimulus characteristics, reliability and diagnostic potential of the tests are examined. Several particularly interesting clinical cases (one closure of a branch retinal arteriole) and two senile macular degeneration patients) are presented for illustrative purposes. In addition, a tentative 'working hypothesis' is presented as a basis for extensive future analysis of various clinical populations.

Aged↗
PubMed1975

A preliminary report on the supraoptic nucleus and control of intraocular pressure.

Four animals received unilateral optic nerve sections which ablated that eye's rise in intraocular pressure in response to water drinking. Bilateral supraoptic nucleus lesions in two animals resulted in ablation of the other eye's response to water drinking. Both animals showed histopathologic proof of the lesion site. Two animals received sham operations for the supraoptic nucleus lesions with no change in their differential response to water drinking. This report gives preliminary evidence of the hypothesis of a supraoptic nuclear control mechanism of intraocular pressure.

Animals↗
PubMed1975

Degenerative choroidal sclerosis with a peculiar bilateral pattern.

A 60 year-old black man when seen in consultation for foreign body sensation and presbyopic complaints was noted on ophthalmoscopy to have bilateral pigment epithelial defects. These defects were curiously symmetrical and there were visual field defects corresponding to the areas showing loss of pigment epithelium. The electrooculogram was abnormal and fluorescein angiography showed normal large choroidal vessels but totally absent choriocapillaris in the involved areas and abnormal pigment epithelium at the edge of the defect.

Choroid↗