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Biomedical subjects

C R SHAW

Publications and source records attributed to C R SHAW.

At least 19 recordsLinked to original sources

AUTOSOMALLY DETERMINED POLYMORPHISM OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN PEROMYSCUS.

Glucose-6-phosphate dehydrogenase commonly occurs in at least two forms in most tissues of the deer mouse, Peromyscus maniculatus, as demonstrated by starch-gel electrophoresis. An autosomally determined genetic polymorphism in one of the enzymes was discovered. A hybrid molecule occurs in the heterozygote; this suggests a dimeric structure of this enzyme.

Animals↗

Hormone-induced esterase in mouse kidney.

Starch-gel electrophoresis of an extract of mouse kidney disclosed that an esterase is present in mature males but absent in females and immature males. When testosterone was injected for 7 days the enzyme could be detected in kidney extracts obtained from both female and young animals. Hence the enzyme may be a hormone-induced one.

Animals↗

New genetically determined molecular form of erythrocyte esterase in man.

An altered molecular form of erythrocyte esterase was discovered in hemolysates from two males and one female in three generations of the same family. This indicates that the alternate enzyme form is under the control of a single autosomal gene. Evidence suggests that the atypical esterase is a variant form of erythrocyte carbonic anhydrase.

Carbonic Anhydrases↗