PubMed Health⌕ Search

Biomedical subjects

C R Silva-Netto

Publications and source records attributed to C R Silva-Netto.

35 records · Page 2Linked to original sources

Adrenergic stimulation of the lateral hypothalamic area on sodium and potassium excretion.

The effects of adrenergic stimulation of the lateral hypothalamic area on sodium and potassium excretion were studied in rats bearing implanted cannulae. When noradrenaline was injected into several points of the lateral hypothalamic area, a dose-related increase in natriuresis and kaliuresis was observed. Rats previously injected through the same cannulae with alpha (Regitine) or beta (Propranolol) blocking agents showed different natriuretic responses when injected with noradrenaline. It was observed that the normal noradrenaline-induced natriuresis was abolished by the alpha-adrenergic blockers, while beta-adrenergic blockers increased the response. Intrahypothalamic injection of Isoproterenol, and activator of the beta-adrenergic receptor, induced a decrease in natriuresis, kaliuresis and urinary volume. In contrast, injection of Metaraminol, an alpha-adrenergic agonist, caused an increase in sodium and potassium excretion and a reduction of urinary volume. Drugs blocking the destruction of noradrenaline or its reuptake by the presynaptic nerve endings potentiated 2-fold the action of 20 nmol of noradrenaline. These experiments provide good evidence for the existence of an adrenergic mechanism consisting of alpha and beta receptors which works antagonistically on the regulation of sodium and potassium excretion. The excretion on the two electrolytes is stimulated by the alpha-adrenergic system, and inhibited by the beta-adrenergic system.

Animals↗

[Restorative dentistry in a community center. 10-year report].

It is reported the results of voluntary odontological assistance in the Community Center of the Methodist Church of Vila Virginia. In a period of ten years the relation patient/dentistry student was an average of 23.08. Of the procedures, 69.9 per cent were amalgam restaurations and 30.1 per cent with silicate cement or resin. This is an important extracurricular activity for the student, in the sense that it helps improve his techniques. On the other hand, although restricted in time, this work has been important for the oral health of the community. Uniterms: voluntary extracurricular activity; amalgam, silicate or resin restaurations.

Community Dentistry↗

[Oral hygiene in university students].

The family income of students entering the University suggests that they should be aware of basic rules of oral hygiene. Thus, oral hygiene was evaluated in a study conducted on 336 1st-year students enrolled in the Pharmacy and Dentistry Course of Ribeirão Preto, USP. The results showed that 42% of the students consult a dentist twice a year; the frequency of tooth brushing was four times a day, with no difference between the use of soft (48%) and medium (49%) brushes, and brushing time was 1 to 5 min. The students use dental floss (87%) and rinse their mouth with Cepacol (37%), and females brush their tongue at higher frequency (70%). Fifty-two percent of the students reported the occurrence of gingival bleeding when they brush their teeth.

Adult↗

[Factors that alter taste perception].

Dysfunction of taste perception is a significant problem for many individuals. Taste anomalies may affect health not only by directly affecting liquid and solid food intake, but also by creating a state of depression due to the loss of an important source of pleasure. Many factors alter taste perception, such as lesions of the oral mucosa, cigarette smoking, radiation, chemotherapy, renal disease, hepatitis, leprosy, hormones, nutrition, use of dentures, medications, and aging. Gum or ice chewing may temporarily help loss of taste. Patients should be encouraged to chew their food thoroughly, alternating the sides of the mouth, or alternating different foods. Unfortunately, in many cases there is no cure for this alteration, and patience is then the only possibility.

Age Factors↗

[Experimental hypervitaminosis A in the rat. 14. Morphological and morphometric study of changes in the esophageal epithelium].

Male rats were subjected to hypervitamin A treatment by daily intraperitoneal injections of 150 UI Arovit per g body weight. Another group of rats were injected intraperitoneally with saline solution for ten days and were used as controls. The results indicated that: 1) the body weight of animals treated with excess vitamin A was decreased; 2) histological analysis of the esophageal epithelium in treated animals showed increased thickness, characterizing a picture of hyperplasia and hypertrophy. On the basis of the results obtained, we suggest that excess vitamin A may act on the esophageal epithelium by direct action on the epithelial structures, stimulating and increase of the mitosis, and on the epithelium (mediated by the adrenals), resulting in increased thickness due to the concentration of a larger number of more immature cells. These alterations were more evident in the lower esophageal third.

Animals↗

Changes in urinary electrolytes excretion after injections of ionic solutions into lateral hypothalamic area of rats.

Rats submitted to a chronically implanted cannula into lateral hypothalamic area (LHA) were utilized to study the effect of ionic stimulation of KCl, LiCl and CaCl2, sodium free solutions, on renal water and electrolyte excretion. In a general way decreases in natriuresis and kaliuresis following the injections of solutions into LHA were observed. Furthermore, significant increases in diuresis were noted after the injections of the 0.30 M solutions.

Animals↗

[Morphometric study of changes in the submandibular gland of aging rats. 2. Ducts].

A decrease in rat submandibular gland parenchyma could be observed with increasing age, consequent to an apparent increase in the proportion of intralobular ducts. Signs of acinar atrophy were noted with nuclei of smaller volume. A great variety of nuclear sizes and shapes was also observed. The blood vessels were smaller, and the connective tissue was increased. These histological data were confirmed in part by application of the technique of Chalkley. The granulous duct cell height is smaller in old animals.

Aging↗