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C Ríos

Publications and source records attributed to C Ríos.

62 records · Page 4Linked to original sources

[Functional prognosis of stroke patients after 3 months: determining factors].

OBJECTIVE: To analyze the factors involved in the functional prognosis of stroke patients three months after onset. PATIENTS AND METHODS: We made a prospective study of 288 patients with non-transient strokes who had been admitted consecutively to our hospital. Data was collected on a standardized questionnaire: age, sex, risk factors, latency of admission, interval of neurological attention (INA), severity of defect (classified on the Scandinavian scale: slight-moderate: SSS > 30/serious: SSS < or = 30), stay in hospital, development of complications and previous quality of life, after seven and ninety days. Two groups were considered according to Barthel's index (BI): acceptable recuperation: BI > 60 and poor recuperation BI < or = 60. RESULTS: The average age was 70.72 years and the latency of admission was 9.71 hours. After three months the functional prognosis was good in 145 patients. On bivariate analysis the latency of admission, severity of the stroke, age, development of complications, INA and BI, one week later were significant. Multivariate analysis confirmed as independent indicators of poor prognosis after 90 days: advanced age of the patient (p = 0.006), the development of complications (p = 0.0235), serious neurological defect (p = 0.0274) and the BI after seven days (p = 0.006). CONCLUSIONS: Advanced age of the patient, the extent of the defect and appearance of complications whilst in hospital were associated with poorer quality of life after three months. The INA > 6 hours also had a negative influence, although it was not confirmed to be an independent variable.

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[Working memory and complex activities of everyday life in the initial stages of Alzheimer's disease].

INTRODUCTION: Evaluation of the working memory (WM) permits analysis of the degree of anterograde amnesia and fixation deficit present in patients with Alzheimer s disease (AD). Complex activities of everyday life (AEL) are also affected early. There is a close relation between the degree of cognitive deterioration and loss of functional competence in AEL. OBJECTIVE: To analyze the degree of memory loss and performance in carrying out complex AEL in patients with AD and mild cognitive disorder. PATIENTS AND METHODS: Evaluation of functional disorder, using Pfeffer s functional activity questionnaire (FAQ), and cognitive evaluation, using the WM examination protocol in a group of 36 patients. RESULTS: In the total MT (4.2+/-5.7) there were significant differences between patients with age associated memory impairment (AAMI) (11+/-7) and possible EA (3.2+/-4.6) and between AAMI and probable AD (2.8+/-4.8). The functional evaluation of the AEL (FAQ) gave a mean of 8.5+/-7.1. There were significant differences between probable AD (11+/-8) and possible EA (6+/-4) with the group AAMI 1+/-1.8. There was significant correlation between FAQ and total WM ( 0.70, p= 0.0001). It was found that patients with high FAQ scores had lower total WM scores. CONCLUSION: FAQ and WM have high correlation and are useful instruments for the evaluation of patients with cognitive deterioration at the initial stages.

Activities of Daily Living↗

[Cerebral gliomatosis. A report of three cases and review of the literature].

INTRODUCTION: Cerebral gliomatosis is an infiltrating, non destructive process of glial type, with a diffuse growth pattern and great clinical variation in the initial symptoms. Confirmation of the diagnosis requires histological study of the lesion showing infiltration by well differentiated mature astrocytes (atypical forms are rare). We report three cases diagnosed by our department over the past five years. CASE REPORTS: Case1. A 64 year old man presented with olfactory crises and right homonymous hemianopsia. On cerebral MR there was an extensive left occipital cortico subcortical lesion infiltrating the genum of the corpus callosum, with irregular uptake of contrast material. CASE REPORT 2: A 68 year old woman was admitted complaining of paresia of her right arm which had worsened over the past two months. On MR there was an extensive left paraventricular subcortical lesion, involving the anterior temporal and capsulo lenticular regions. Case 3. A 63 year old woman complained of staggering gait and headache. On examination she had a right facial palsy and intention tremor of her right arm. All the patients died. In all cases stereotactic biopsy confirmed the diagnosis of cerebral gliomatosis. CONCLUSIONS: Cerebral gliomatosis is an infiltrating glial disorder with a poor prognosis. The clinical diagnosis is suggested on cerebral MR studies and confirmed on histological studies.

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[Opercular syndrome of vascular aetiology].

INTRODUCTION: Facio linguo masticatory paralysis resulting from bilateral lesion of the anterior opercular region, known today as Foix Chavany Marie syndrome, appears very frequently in adult patients as a consequence of generally ischemic vascular lesions, which directly affect the Rolandic opercula or the subcortical area surrounding them. However, forms that are secondary to infections, neoplasias and even unilateral lesions have been reported. CASE REPORT: Female patient, aged 70, with unknown auricular fibrillation, which started suddenly with right faciobrachial paresis secondary to a left striated ischemic infarction. Approximately 24 hours after beginning intravenous heparinization, the patient presents anarthria, facial hypomimia without asymmetries, dysphagia above all for liquids and bilateral lingual paresis. Extraoccular movements, blinking and corneal reflex were normal. Understanding of spoken and written language was maintained and there were no apraxias or agnosias. Neurological exploration was compatible with an opercular syndrome (OS). Urgent brain CT revealed the existence of a right cortiico subcortical temporal haemorrhage, in addition to the prior contralateral ischemia. The association of both lesions, ischemic and haemorrhagic, mirrored, justified all the symptomatology. DISCUSSION: Anterior OS is characterised by a bilateral voluntary central paresis of the muscles innervated by the 5th, 7th, 9th, 10th and 12th cranial pairs with preservation of emotional or automatic mobility. Underlying mechanisms are also discussed.

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["Household items" : an alternative task to "animals" in the assessment of semantic verbal fluency: a validation study].

INTRODUCTION: The semantic verbal fluency (SVF) is usually evaluated with the task animals in 1 minute . This is a test widely applied in the screening of cognitive impairment. In our best knowledge there are not other alternatives categories for this task validated in our environment (Spanish as mother tongue, Spain). OBJECTIVE: To validate the category households items as an alternative parallel task to animals in the assessment of SVF. PATIENTS AND METHODS: Prospective assessment of two categories (animals and household items) in two groups: normal controls and patients with Alzheimer s disease (AD). RESULTS CONTROL GROUP: n= 22 (13 M, 9 W); age: 73 5 years, education: 12 5 years; MMSE MEC 35: 30 4; Animals : 15 4. Percentile distribution 10th: 11; 50th: 15; 90th: 20; household items : 17 4. Percentile distribution: 10th: 12; 50th: 17; 90th: 22. AD group: n= 24 (9 M, 15 W); age: 74 5 years; education: 11 5 years; MMSE MEC 35: 17 8; Animals : 6 3. Percentile distribution: 10th: 2; 50th: 6; 90th: 9; household items : 6 4. Percentile distribution: 10th: 1; 50th: 6; 90th: 11. It is observed a positive correlation between the two categories (Spearman s Rho: 0.83, p< 0.0001). CONCLUSIONS: Both SVF categories had a similar distribution and a high correlation. This findings demonstrated the validity of the household items as an alternative and parallel form to animals in the assessment of SVF in patients with cognitive impairment or dementia.

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Changes in manganese and small cobalt blood levels of lead-exposed workers.

Blood levels of manganese and cobalt were analyzed with graphite furnace atomic absorption spectrophotometry in three groups of workers: non-exposed, middle-exposed and heavy-exposed to lead from five lead-acid battery factories located in Mexico City. Manganese levels were significantly higher in the heavy-exposed workers than in the non-exposed subjects. Cobalt in blood concentrations was found to be lowered in both middle and heavy exposed workers as compared to the control group. The significance of these findings is discussed in terms of the possible mechanisms underlying these observations.

Adult↗