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C Ramírez

Publications and source records attributed to C Ramírez.

92 records · Page 6Linked to original sources

[Levels of anti-Gal antibodies in persons infected and non-infected with Trypanosoma cruzi. Probably induced by bacteria and by the parasite].

Antibodies levels against Gal alpha 1,3 Gal epitopes were studied in 407 human sera (92 chagasic and 315 non-chagasic), by means of hemagglutination with rabbit erytrocytes reactivity of serum having high titres of anti-Gal antibodies in presence of Escherichia coli and Serratia marcescens antigen was studied by immunoelectrotransference. Finally, using a purified anti-Gal antibody, Gal alpha 1,3 Gal epitopes were identified in metacyclic forms from 12 high Andean Chilean strains of Trypanosoma cruzi. Among the chagasic sera, it was demonstrated that in 63 (68.5%) were detected antibodies anti-Gal at the same or higher titer than 1:1,600; while i the non chagasic sera only 49 (15.6%) showed and anti-Gal response at similar titers. Immunoelectrotransference showed that the sera of people infected with T. cruzi recognize antibodies present in E. coli and S. marcescens, which reinforces the idea that at least in part, these bacterias would be capable of stimulating these responses. The autoradiographic analysis using purified anti-Gal antibodies, showed differences in the Gal alpha 1,3 Gal epitopes expressed in the different strains of T. cruzi. These results suggest that anti-Gal antibodies could have a real significance on the natural immunity mechanisms and protection of human infection with T. cruzi.

Animals↗

[Infection by intestinal protozoa and helminths in schoolchildren from riverside sectors, with different fecal contamination levels, of Valdivia River, Chile].

During 1993, the prevalences of infection by intestinal protozoa and helminths (IPH) in the riverside schoolchildren population of two sectors of Valdivia river, with different levels of fecal contamination, were compared in relation to their contact with river water (swimming, bathing) and basic sanitation elements (BSE) of their houses: feces and garbage disposal, and water supply. Populations of children from sectors A (n = 418), with significatively greater (SG) total coliform most probable number (MPN), and sector B (n = 400), were examined. PAFS test was used for the stool examination of one sample, from each child. The global prevalence of infection by IPH was similar in A (74.8%) and B (72.5%) sectors. From 10 identified IPH, only Entamoeba histolytica and Hymenolepis nana showed prevalences of infection SG in sector A, than in sector B. The contact of the children with the water of the river showed association with SG prevalences for E. histolytica, Entamoeba coli and Endolimax nana in sector B and for E. histolytica in sector A. No sanitary condition for the different BSE contributed to SG prevalences for E. histolytica, Ascaris lumbricoides and Trichuris trichiura in both sectors, and for E. coli in sector B. The contact with the river water and the different BSE contributed to prevalences SG in 5 and 3 IPH in sectors B and A, respectively. The results suggest that a project in study for the development of a treatment plant of wastewater in sector A, could contribute to control infection by IPH. But, this measure must be associated with improvement of the BSE, health education, and application of chemotherapy measures for geohelminthosis in both sectors.

Adolescent↗