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C Ringwald

Publications and source records attributed to C Ringwald.

5 recordsLinked to original sources

Long-duration stress. Immediate and late effects on small and large bowel motility in rat.

No extensive information exists in literature concerning the late or residual effects of stress on motility of small bowel and colon. Moreover, the duration and magnitude of the intestinal motor response to stress are still ignored. Therefore, the aim of our work was to determine, in rat, the effect of long-duration stress induced by restraint on the motility of small bowel and colon. Observations were made during physical restraint and 60 h later. Bipolar electrodes were implanted on the gastrointestinal serosa from the pylorus to the sigmoid colon in male Wistar rats. Electromyographic (EMG) recordings were made during fasting state, and a control EMG recording session was performed during 12 hr, followed by a 12-hr recording during restraint stress. After a 60-hr resting period, another EMG recording session was performed during 3 hr. During stress in the pylorus and small bowel, the recurrence of migrating myoelectrical complexes (MMCs) was immediately interrupted and replaced by a continuous and irregular activity. The motility index (number of spike bursts/10 min) was augmented rapidly on the jejunum and ileum, but it increased only gradually on the pylorus. Only on the transverse colon were the number of spike bursts/hour and their relative duration increased after 7 hr of physical restraint. In contrast, the sigmoid colon displayed a gradual decrease in the relative duration of contractile activity during the first 6-7 hr of stress. At 60 hr after stress in the pylorus and small bowel, a normal control motor activity was restored (MMC, motility index) on the jejunum and on the ileum, but the motility index on the pylorus was decreased.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Ag/AgCl electrode assembly for thin smooth muscle electromyography.

An electrode assembly for in vivo recording of the electrical activities of thin muscular layers is described. It comprises an active electrode surrounded by a ring, which avoids the recording of interfering signals. An improved technique for chlorinating the silver electrodes is presented: a partial electrolytic removal of an initial thick deposit is performed. This decreases the impedance, and lowers the ageing degradation of the electrodes in vivo. Recordings of extremely low frequency signals are allowed, whereas standard Ag/AgCl electrodes are inefficient when recording signals in the frequency domain under 0.1 Hz. The technical features which are described can be adapted to any Ag/AgCl electrode developed for in vivo measurements.

Animals↗