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Biomedical subjects

C Rioux

Publications and source records attributed to C Rioux.

At least 73 records · Page 4Linked to original sources

[Associated lesions in closed injuries of the thorax: right bronchial rupture, rupture of the right subclavian artery, and bilateral fracture of the 1st rib].

A patient presented with rupture of right bronchus associated with rupture of the homolateral subclavian artery (diagnosed secondarily at the false aneurysm stage) and bilateral fracture of the 1st rib. Two stage repair operation provided lasting recovery. This case is used as a basis for emphasizing the diagnostic problems raised by combined endothoracic lesions, the need for systematic investigation of possible presence of a lesion of subclavian artery in patients with fracture of 1st rib, and finally various operative tactics (in the framework of false aneurysms of proximal subclavian vessels).

Adolescent↗

[Surgery of calcified aortic stenosis in patients aged 70 and over. Immediate results. Apropos of a series of 229 cases].

229 patients aged 70 or over with aortic stenosis (AS) underwent surgery between January 1972 and July 1983 (21.8% of 814 cases of AS operated on during the same period). The Björk Shiley prosthesis was used at the beginning of the series (115 cases, 50.2%), until bioprostheses became the treatment of choice in this age group. Overall operative mortality in the series was 10.9% (25/229). Analysis shows a very marked reduction in recent years: from 15.6% between 1972 and 1977, to 5.8% in 1982-3. Improvement can be attributed in part to the technical progress in myocardial protection. Patient age is a very significant factor in the prognosis. Progress in surgery, together with that in anaesthetics and intensive care, justifies operation in these elderly and incapacitated patients whose general and neurological condition is well preserved.

Age Factors↗

Colorimetric determination of catechol siderophores in microbial cultures.

A highly sensitive spectrophotometric method for the selective detection of catechol compounds such as catechol siderophores (e.g., enterobactin) is described. The basis of the method involves the ability of the vicinal aromatic hydroxyl groups under acidic conditions to bring about a reduction of Fe3+ (from ferric ammonium citrate) to Fe2+. Detection of Fe2+ in the presence of Fe3+ is made with 1,10-phenanthroline under previously established conditions. The assay mixture is heated at 60 degrees C for 1 h to accelerate the development of color which is subsequently measured at 510 nm. The Beer-Lambert law is obeyed over the range of 0.16 to 60 microM 2,3-dihydroxybenzoic acid. Compared to the Arnow nitration method, the assay is more responsive, is approximately seven times more sensitive, and is effective with catechols substituted at positions 3 and 4. The method gives positive results with catechols such as DL-DOPA, L-dopamine, (+/-)-epinephrine, and DL-norepinephrine. Very rapid color development is obtained with ascorbic acid and p-diols, while m-diols are poorly detected. Low degrees of reactivity are shown by hydroxylamino and hydroxamate compounds. Phenolic, sulfydryl, indolyl, and quinonyl derivatives do not interfere with the reaction. The method has been adapted to determine catechol compounds in the culture medium of bacterial cells grown at different iron concentrations.

Catechols↗

[Immunological changes following heart surgery under extracorporeal circulation (author's transl)].

Post-operative immunological changes were studied in 40 patients undergoing heart surgery. Tty-five patients were operated upon under extracorporeal circulation (ECC), and 15 without ECC. Immunological investigations were performed before, immediately after the operation and again 7 days later. The post-operative changes recorded were early decrease in IgG and IgM followed by a rise in IgM, transient lymphocytopenia affecting mainly T lymphocytes and delayed increase in complement (CH50, C2, C3). These changes were comparable in both groups of patients and therefore seemed to relate to the operation itself rather than to the ECC. It may be concluded that ECC does not appear to increase the risk of post-operative infection by depressing immune defence mechanisms.

Adolescent↗

[Surgery of aneurysms of the abdominal aorta. Clinical study and surgical results. Apropos of a series of 54 cases].

54 patients with an abdominal aortic aneurysm were hospitalized between 1969 and 1980 in the Clinic of Cardiovascular and Thoracic Surgery at Rennes (Pr. Y. Logeais): 35 were ruptured aneurysms, 19 non-ruptured. The average age of the patients was 70.6 years. 48% of patients showed signs of atheroma in at least one other site. 24% had arterial hypertension. Arteriography was carried out in 51.5% of the non-ruptured aneurysm cases and in 26% of the ruptured cases. Both ultrasound and tomography are regarded presently as very useful tests. The intervention carried out in 41 patients always involved the insertion of a by-pass graft (aortic only in 7 cases; aorto-biiliac in 19 cases; aorto-bifemoral in 15 cases). Mortality was 7.7% for the non-ruptured aneurysms. 59% for the ruptured aneurysms, the deaths above all being related to the degree of visceral ischaemia. Secondary mortality was comparable for all the aneurysms operated on. More than 80% of patients were surviving 5 years after surgery.

Aged↗

[Myxoma of the mitral valve in a child. Apropos of an operated case].

The case of an 8 year old child with a symtomless murmur of mitral incompetence is reported. Echocardiography showed the presence of an intracardiac tumour, a mass of dense echos between the two mitral leaflets being recorded; multiscan examination suggested insertion on the anterior mitral leaflet. The tumour and its pedicle were resected, causing some loss of valvular tissue, which required repair with a strip of pericardium. This would appear to be the first reported case of mitral valve myxoma in children. Left atrial myxoma, the commonest cardiac tumour, is rarely observed before 15 years of age; insertion on the mitral valve itself is rare at any age. The site of insertion is determined by quite separate echocardiographic criteria compared to left atrial myxoma. This is important as surgery may sacrifice the mitral valve, and mitral valve replacement may be needed; valvuloplasty should be attempted in this age group, despite the risk of tumour recurrence, which is porbably greater with this unusual location.

Child↗

[Ventricular branches of the circumflex artery of the heart].

Because of the great number of anatomic descriptions, and because of the variability of the nomenclature, the authors realized three studies: anatomical, radiological, and surgical studies of 198 hearts (150 dissections and 148 angiographies). There are 3 groups of collateral branches for the left ventricle: --The lateral branch (existing in 49 per cent of the cases), beginning after a short space with often an intra-myocardial segment, and running obliquely on the pulmonary surface of the left ventricle. --The lateral and inferior branch (existing in 38 per cent of the cases), situated just between the pulmonary and diaphragmatic surface of the ventricle, and perpendicular to the coronary sulcus. --The inferior or posterior branches (existing in 59 per cent of the cases), which are parallel to the inferior (or posterior) interventricular sulcus, on the diaphragmatic surface of the heart.

Coronary Angiography↗

[Dimensions of the aortic ring. Anatomic and surgical study of 2 series of patients].

Both surgical (236 aortic valve replacements) and anatomical (62 dissections) studies have defined the aortic annulus diameter. Measurements (23.5 mm for women; 26 mm for men) are more considerable than established values. Furthermore, surgical study allows the authors to compare these results to several variables, more especially corporeal surface and stature: the height's increase perhaps explains the large sizes discovered.

Aorta↗

[Agenesis of the left pericardium. Apropos of 3 anatomo-surgical observations].

After a short review of the history and the frequency of this malformation, the authors report three cases of pericardial defect: two cases of partial defect, and a case of complete absence (these three patients have been operated); these observations allow the authors to insist on the difference between the complete absence (often very well tolerated) and the partial defect, which exposes to left atrial appendage's incarceration (and sometimes sudden death). The classification based on the extension of the lesions is then considered, and the usual aspect of each type is described. The embryologic findings can explain the higher frequency of left pericardial defects.

Adolescent↗

[Deep femoral artery. Anatomoradiological study].

After a double study (anatomical--50 dissections--and radiological--100 arteriograms) the following points can be stressed: the femoral tripod is only found in 38 per cent of the cases. One or several nutrient arteries of the thigh originate often separately (62% of cases). Their origine is situated highup in a number of cases (at 3 cm below the inguinal ligament). The collateral network develops from each of the arteries forming a complete "profunda femoris system". Two surgical consequences deserve to be underlined: 1. The approach to all the branches is possible by a transverse incision in the fold of the groin. 2. Surgical revascularisation must concern the whole of the "profunda femoris" network.

Collateral Circulation↗

[Atheromatous stenosis of the left coronary trunk. 28 surgical cases].

22 patients with atheromatous narrowing of the left coronary trunk underwent surgery between 1969 and 1974. Most of these patients had severe and incapacitating angina pectoris. The clinical features are readily explained by the size of the diffuse anatomical lesions, which are to be found on the left coronary trunk as well as on the three coronary vessels themselves. This series has not confirmed the serious risk of surgery in such cases, as there were no operative deaths. Secondary mortality was low (9%), and the 20 survivors (average length of follow-up: 26 months) were mostly (18/20) in an excellent condition functionally. These facts have lead us to advise surgery whenever possible.

Adult↗

[Primary bacterial aneurysm of the aorta. 4 cases].

The causal agent was a Salmonella in three cases and a Pseudomonas Aeruginosa in one case. In these four patients there was no evidence of endocardities and the causal germ was verified by the bacteriological cultures of the anevrysmal lesions and/or by the blood cultures. In one patient full recovery was obtained by surgical repair after complete bacteriologic cure.

Aged↗