PubMed Health⌕ Search

Biomedical subjects

C Rodrigo

Publications and source records attributed to C Rodrigo.

68 records · Page 4Linked to original sources

Tenoxicam for pain relief following third molar surgery.

Tenoxicam is a long-acting nonsteroidal anti-inflammatory agent that appears to have the ability to control pain of musculoskeletal origin. A double-blind randomized crossover study was designed to determine the efficacy of tenoxicam for pain relief following third molar surgery by comparing it with paracetamol. Immediately before surgery, 30 Chinese patients with bilateral symmetrically impacted mandibular third molars were given 40 mg of tenoxicam for surgery on one side and 1,000 mg of paracetamol for surgery on the other. Both paracetamol and tenoxicam were efficient as pain relievers after third molar surgery. Tenoxicam had comparable efficacy to paracetamol, but did not provide any advantage in terms of duration of action. The discrepancy between the clinical observation and pharmacokinetic prediction may be related to the strong serum binding property of tenoxicam.

Acetaminophen↗

A comparison of paracetamol and diflunisal for pain control following 3rd molar surgery.

A double-blind randomised cross-over study to compare 2 regimes of paracetamol and diflunisal for postoperative pain relief following 3rd molar surgery was designed. 35 patients received one of the regimes at one visit and the alternative at the other visit. Both drugs, namely a single dose of 500 mg of diflunisal given preoperatively or 2 doses of 1000 mg of paracetamol, given preoperatively and 4 h postoperatively, produced adequate pain relief, without the need for supplementary analgesics during the 10-h test period. The differences in the mean overall pain scores in the 2 regimes were not statistically significant.

Acetaminophen↗

[Knowledge and treatment of hypertension in La Plata, Argentina].

Hypertensive subjects, aged 15-75 years, detected by the survey of Prevalence of Hypertension in La Plata, were evaluated to settle the rates of awareness, treatment, control status and the efficacy of pharmacologic therapy (EPT). The survey was composed of 2,090 subjects when the threshold of hypertension was equal to blood pressure (BP) greater than or equal to 140-90 mm Hg and of 1,203 subjects with a BP threshold greater than or equal to 160-95 mm Hg (Table I). The rates of awareness, treatment and control for the 140-90 mm Hg threshold were 43.97%, 33.06%, 4.9%, respectively, and the EPT was 15.03%. For the 160-95 mm Hg threshold the rates were 69.41%, 54.44% and 27.76% and the EPT was 48.32% (Table 2 and Fig. 1). The awareness and treatment rates for women were greater than those for men (p less than 0.0005) (Table 2). The EPT was similar in both sexes when the 140-90 mm Hg threshold was used while it was greater in women than in men with the 160-95 threshold (p less than 0.014) (Table 2). The rates of awareness and treatment increased with age and with the severity of the disease (Table 3-5). The EPT decreased from 85.71% in the 15-24 yr. age group to 10.56% in the 65-75 yr. age group (Table 4). Although the rates of awareness and treatment of hypertension found in La Plata were similar to those found in USA, the control of the disease was lower.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Infantile idiopathic hypercalciuria, high congenital myopia, and atypical macular coloboma: a new oculo-renal syndrome?

Four cases of infantile idiopathic hypercalciuria with high congenital myopia and atypical macular coloboma are discussed; two of them are brother and sister. The eye examination shows bilateral congenital myopia of more than 10 diopters in every case. In the fundus examination, there is a bilateral macular colobomatous lesion in two of them and monocular lesion in the remaining ones. Hypercalciuria is considered to be due to renal tubulus malformation. The macular atypical coloboma etiopathogenesis is discussed, with comment on the malformative, dystrophic and inflammatory hypothesis, having discarded the usual inflammatory etiologies. We have only found two cases similar to these in the literature, Given the relative scarce occurrence of each of the three mentioned clinical features we suggest the possibility of a new oculo-renal syndrome rather than a coincidental association.

Adolescent↗

[The relation between the clinical symptoms and the findings on magnetic resonance in children with periventricular leukomalacia].

OBJECTIVES: To assess whether there is a relationship between the various clinical symptoms and imaging findings on MR in children with periventricular leukomalacia (PVLM). PATIENTS AND METHODS: We made a retrospective study of 41 consecutive paediatric patients, 19 boys and 22 girls, with an average age of 30.5+/-19 months (range 8 84 months) who had been diagnosed as having PVLM and studied using MR, recording imaging, clinical and epidemiological data. RESULTS: The MR images showed areas of gliosis in all the children (few foci in 68.3% and multiple foci in 31.7%), with cysts in 22%. The changes were seen mainly in the parietal and occipital regions, were bilateral and symmetrical in 80.5%, with ventricular dilatation in 75.6%, atrophy of the parenchyma in 48.8%, Wallerian degeneration in 7.3%, delay in myelination in 31.7%, lesions in the optic radiations in 9.8%, thalamus 12.2% and anomalous venous drainage in 2.4%. The overall degree of involvement on MR was severe in 43.9%, moderate in 31,7% and mild in 24.4%. There was a history of perinatal foetal distress in 56.8%, hyaline membrane disease in 40.5%, intracranial hemorrhage in 35.1%, psychomotor retardation in 58.5%, motor retardation in 29.3%, and squint in 22%. A significant relationship was found only between acute foetal distress and lateralization of the lesions (p= 0.038) and the presence of parenchymatous cysts (p= 0.024). CONCLUSION: The patients with a history of foetal distress had a greater tendency to symmetrical, bilateral involvement with cysts in the white matter of the brain. It was not possible to establish a model for classification of the overall involvement using MR and the data recorded. The imaging findings were not related overall to the patients symptoms.

Child↗