PubMed Health⌕ Search

Biomedical subjects

C S Boye

Publications and source records attributed to C S Boye.

35 records · Page 2Linked to original sources
PubMed1995

[Antibacterial activity of essential oils from mint in Senegal].

Three species of the Mentha gender are found in Senegal under the name of "Nana", and are essentially used in tea and juices as flavour. The aerial parts of the three species (common mint, mentholated mint and "fass" mint) have been harvested two months after they have been sown and the extraction of the essential oils was done by carrying them away with water vapour by hydrodistillation. The essential oils were used to study the antibacterial potency (typing of the Minimal Inhibitory concentrations-MIC) by the agar dilution method. This survey has been carried out on ten bacterial strains among which three (3) ATCC reference stubs, and on one fungus (Candida albicans). The MIC found was less than 25 mcg/ml; these results show an antibacterial potency according to the NCCLS norms (MIC < 256 mcg/ml). The tested strains were more sensitive to the essential oil of the "common mint" than the "fass mint". Pseudomonas aeruginosa was the most resistant strain and Candida albicans the most sensitive agent.

Anti-Bacterial Agents↗
PubMed1995

[Epidemiological and anatomo-clinical features of extra-uterine pregnancies at the Dakar University Hospital Center].

It is the prospective study of 226 cases of operated ectopic pregnancies, in order to draw the epidemiological outline of such an affliction adn find out the possible etiologies. During this study, 107 swabs were anatomically exploited. An analysis of the results reveals the high frequency of disrupted ectopic pregnancies (over 90%). The ampullary localization exists in 73.45% of the cases. In the histological level, in 82.70 of the cases, the tubal pregnancy has been associated with a salpingitis or malformed lesions. The death rate is about 2.65%. In other respects, it appears that the limits of echography are actual, hence the importance of basic clinic, that mutilating surgery remains prevalent; histology also plays an unavoidable part in the diagnosis.

Adolescent↗
PubMed1994

[Importance of culture media choice in the isolation of Haemophilus ducreyi. Experience in Senegal].

Genital ulcerations typify one of the major reasons clients seek STD consultation in developing countries. The usual etiologies are syphilis, chancroid and herpes. The ideal diagnostic approach is to undertake complete laboratory examination that are rarely possible in structure destitute of laboratory analysis possibilities which is the case for most of the STD transmission agents. Chancroid is caused by Haemophilus ducreyi, a short Gram negative bacteria. The bacteriological diagnosis is based on direct examination, isolation and identification of the bacteria. The nutritive exigence of the bacteria required 3 medium of isolation (PPLO base Pasteur), GC base (GIBCO) and Muller Hinton base (Becton & Dickinson, with "chocolate" agar) have been tested from the chancre samples of 108 male patients who had a median age of 31 years. Direct exams were positive in 66 cases (61%) and culture exams positive in 53 cases (49%). The Muller Hinton base with "chocolate" agar produced the best results and seems to be the medium of choice for isolated strains in Senegal. The culture mediums currently used in Europe are apparently inappropriate for the germ culture in Senegal. We have also observed that all the isolated strains were producers of beta-lactamase. Antibiotic treatment before the sample swab is taken seems to have an inhibiting effect on the culture. Direct examination with a sensibility of 94.3% and a specificity of 70.9% remains sufficient in routine presumptive diagnosis in endemic areas.

Adult↗
PubMed1993

[Urinary bacteriology in the elderly in the tropical zone: results of 5 years of activities at the CHU of Fann in Dakar].

The authors report a retrospective account on 5 years (1987-1991) studied on 300 specimen of urine, coming from subjects aged 65 or more and having been submitted to bacteriologic examination in Dakar, Senegal (microscopic examination, counting, isolation, identification of bacteria, antibiotic tests). On the whole, 8150 samples of urine were recorded during the same period in the Laboratory of Bacteriology (CHU de Fann). The results obtained show a particular exposure of the old subjects to urinary tract infection (37%, against 23% in subjects aged less 65 years). The isolation of bacteria was not attached to sex. E. coli and Klebsiella sp. are the most frequently isolated in urine. The most efficacy antibiotics on these agents are the Cepholosporins, the Aminosids, Nitroxolin and Oxolonic Acid.

Age Factors↗
PubMed1993

[Antibiotic sensitivity of Salmonella strains isolated in a pediatric population in Dakar. Research of beta-lactamase and plasmids].

114 strains of Salmonella were isolated from many samples in the Pediatric Hospital (Hôpital d'Enfants Albert Royer) of Dakar between January 1985 and December 1991. The sensibility to antibiotics were tested, and we studied the production of beta-lactamase and the presence of plasmids in the resistant strains. 27 serovars of Salmonella were identified and Salmonella typhi predominates with 45%. Only 28% of the strains were susceptible to all of the antibiotics, and 17% were found multiresistant; 8% of the strains produce beta-lactamase and plasmids were found in 6 multiresistant strains.

Anti-Bacterial Agents↗
PubMed1992

[Evaluation of Vibrio cholerae isolation over 10 years in CHU Fann].

A retrospective study, concerning ten thousand five hundred and sixty five (10,565) stool samples examined from 1981 to 1990, was done at the Bacteriology Laboratory of Fann University Hospital, Dakar (Sénégal). One thousand and six hundred and eighty (1680) enteropathogen agents were detected (15.9%), five hundred ninety two (592) of which were vibrio cholerae. The quasi totality strains of the vibrio cholerae (99.8%) belonged to the Ogawa serotype; they were isolated mainly during the hot and raining season. Young male adults were the most infected. Most of the strains revealed sensitive to Sulfamids and Tetracycline.

Adult↗
PubMed1991

[Salmonellosis: evaluation of 606 strains isolated in Dakar].

From 1979 to 1982, 606 strains of Salmonella have been isolated in the Laboratories of the CHU of Dakar, Senegal. The endemics serotypes are S. typhi (73%), S. enteritidis (5% and S. typhimurium (5%). Among the epidemics serotypes of Salmonella, the more commonly isolated is S. ordonnez (10%). These four serotypes represented 93% of the strains of Salmonella. Seventy per cent of the strains had been isolated from patients aged under less than twenty years. The epidemic serotypes provide essentially from infant. Five antibiotics among the eighteen tested, have inhibited 100% of Salmonella. A multiresistance to more than five antibiotics have been observed for sixty four strains (11%). Some strains of S. typhi (4%) are resistant to the chloramphenicol and three of them were multiresistants; this may result from the transfer of plasmidic's resistance of multiresistant epidemics serotypes Salmonella circulating in Dakar. In Sénégal, periodics studies of the epidemiology of Salmonella are justified.

Adolescent↗
PubMed1991

[Neonatal bacterial infections: a retrospective study over 8 years].

In a retrospective study, one thousand and ten miscellaneous samples coming from infected newborns and tested at the bacteriology laboratory of A. Royer Children's Hospital from 1983 to 1991 were reviewed. These samples included 471 blood cultures, 114 pus of various origins, 410 cerebrospinal fluids and 15 urines. One bacterium or bacterial soluble antigens was detected in 294 samples (29.2%). Positivity percentage was 29.2% for septicemias, 68% for suppurations, 17.8% for meningitidis and 33.3% for urinary tract infections. There major species were identified: S. aureus (25.8%), Klebsiella spp (19.7%) and E. Coli (14.6%). Altogether, we isolated 156 enterobacteria (53%), 14 Gram negative bacilli (4.7%) and 124 cocci (42.1%) among which 19 streptococci (A, B, C) and 25 pneumococci. The most efficient antibiotics against all strains were AKN, CTX, CRO and GEN.

Anti-Bacterial Agents↗
PubMed1990

[Urinary infections in gyneco-obstetrical practice at DAKAR U.H.C].

This prospective study seeks to define the epidemiological, clinical and biological boundaries of the danger of urinary infection in women, with a view to facilitating therapy where bacteriological competition is absent. 238 samples taken over a 4 month period revealed 57 bacteriologically positive, i.e. 24%. Urinary infection is particularly associated with women in their 30s, poor, and from a low socio-economic class, with little urinary history. Risk increases for pregnant women during the second quarter. Typical, classical symptoms, each for what it is worth, are to be found in over 75% of the positive samples. The most common germs are enterobacteria particularly sensitive to quinolones, aminosides and 3rd generation cephalosporines.

Adolescent↗
PubMed1989

[Causes of infectious gastro-enteritis in children in Dakar].

Between February 1983 and May 1988, 1,157 stools from children aged under 15 years presenting with diarrhoea and admitted to a paediatric hospital in Dakar, Senegal, were examined for the presence of bacterial and parasitic agents. We looked for Campylobacter and rotavirus in only 245 and 111 samples respectively. Enterobacteria were detected most frequently (162/264; 61.3 per cent). Among these, we found 92 (34.8 per cent) strains of enteropathogenic E. coli; 40 strains (15.1 per cent) of Salmonella spp. and 30 strains (11.3 per cent) of Shigella spp. V. cholerae was present in only 2 faecal specimens (0,7 per cent). Eighty-one (30.6 per cent) parasitic agents were isolated, including a high proportion (13.6 per cent) of flagellae. Campylobacter jejuni and retroviruses were found in 2 (0.8 percent) and 15 (13.5 percent) stool respectively. The frequency with which these enteropathogenic agents were isolated remains in keeping with the global situation usually observed in Dakar for several years.

Adolescent↗
PubMed1989

[Electrophoretypes of the genome of rotaviruses isolated from Senegalese children].

Polyacrylamide gel electrophoresis allowing study of rotavirus genome was applied to 213 faecal specimens from children with acute gastroenteritis living in Dakar area, Senegal. We were able to define an electrophoretype in 41 cases (19.2%). Five different RNA electrophoretypes were shown. The electrophoretype 4 was the most frequent (41.4%). "Long" and "short" electrophoretic migration patterns were found in 36 and 5 cases, respectively. We found 34.1% of electrophoretypes in children aged from 6 to 11 months. The electrophoretypes 1, 3, 4 and 5 have co-circulated throughout the study period (March 1985 to August 1986). No mixed infections were found. Large surveys of this type would allow to evaluate the general situation in Senegal in urban areas as well as in rural areas.

Child, Preschool↗