Olfactory disturbances as the initial or most prominent symptom of multiple sclerosis.
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Adult↗
Biomedical subjects
C S Constantinescu
Publications and source records attributed to C S Constantinescu.
Urinary free kappa light chain levels in chronic progressive multiple sclerosis.
Previous studies have shown elevated levels of free kappa light chains (FKLC) in the urine of patients with relapsing-remitting multiple sclerosis (MS). The levels correlated well with clinical relapses, indicating that they could serve as useful markers of disease activity. In this study, we performed monthly measurements of urinary FKLC in patients with the chronic progressive form of MS, and correlated them with clinical indicators of disease activity, as expressed by Kurtzke's expanded disability status scale (EDSS) and brain magnetic resonance imaging (MRI). We noted wide fluctuations in the FKLC levels, which correlated poorly with EDSS scores or MRI changes. Longer follow-up periods may be needed before definite conclusions can be drawn.
Adult↗
Recurrent migraine and intravenous immune globulin therapy.
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Humans↗
Absence of electromyographically detectable acute neuromuscular transmission defects after intramuscular interferon-gamma administration.
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Action Potentials↗