Biomedical subjects

C S Findlay

Publications and source records attributed to C S Findlay.

5 recordsLinked to original sources

PubMed1994

Optimization by trees on simple adaptive landscapes.

We evaluate the optimizing ability (rate of adaptation) of trees on simple adaptive landscapes. At points away from a peak, there is a strong negative relationship between rate of adaptation and tree precision P, a relationship that is independent of the size of the tree. P measures the variability among trial solutions generated by the tree: high precision trees have low variability, low precision trees have high variability. Near a peak, the situation reverses, with high precision trees showing higher rates of adaptation than low precision trees; however, for all trees, the absolute rate of adaptation is uniformly low. On multiple-peak landscapes, the probability of crossing an adaptive valley from a lower peak to a higher peak is also negatively correlated with tree precision. These results suggest that under a wide range of conditions, trees with low precision are, on average, the best optimizers.

Adaptation, Biological↗

PubMed1992

Phenotypic evolution under gene-culture transmission in structured populations.

I consider a simple model for the evolution of a quantitative character is structured populations when an offspring's phenotype is determined partly by his or her genetic constitution and partly by cultural transmission of the parental phenotype. Analysis of the model indicates that when individual and group selection are in the same direction, phenotypic evolution always proceeds faster under gene-culture vs. purely genetic transmission. When individual and group selection are countervailing, altruistic characters evolve faster under gene-culture transmission when individual selection is weak and migration among groups is limited, with increased individual selection and migration tending to decrease the advantage of gene-culture transmission over purely genetic transmission. Given the prevalence of cultural transmission in higher species, these results suggest that contrary to what is often assumed, group selection may indeed by a potent evolutionary force in the evolution of altruistic characters.

Altruism↗

PubMed1992

Secondary theorem of natural selection in biocultural populations.

The "Secondary Theorem of Natural Selection," an extension of Fisher's fundamental theorem, states that the rate of change in the mean of an arbitrary character in response to selection is proportional to the additive genetic covariance between the character and fitness. Here I derive an expression for the change in the mean value of a trait subject to both genetic and cultural transmission. I start with the one-locus case under generalized mating and cultural transmission from parents to offspring, then proceed to the two-locus case. My results support previous work on the effects of nongenetic inheritance by showing that (i) cultural transmission introduces a timelag in the population response to selection; (ii) with cultural transmission the effects of selection persist even after selection is relaxed; and (iii) cultural transmission can either enhance or retard phenotypic evolution relative to that obtained under purely genetic transmission.

Biological Evolution↗

PubMed1991

Fundamental theorem of natural selection under gene-culture transmission.

A generalized fundamental theorem of natural selection is derived for populations incorporating both genetic and cultural transmission. The phenotype is determined by an arbitrary number of multiallelic loci with two-factor epistasis and an arbitrary linkage map, as well as by cultural transmission from the parents. Generations are discrete but partially overlapping, and mating may be nonrandom at either the genotypic or the phenotypic level (or both). I show that cultural transmission has several important implications for the evolution of population fitness, most notably that there is a time lag in the response to selection such that the future evolution depends on the past selection history of the population.

Animals↗

PubMed1989

Behavioral evolution and biocultural games: vertical cultural transmission.

We consider an evolutionary game model in which strategies are transmitted culturally from parents to offspring rather than inherited biologically. Our analysis yields two noteworthy results. First, biocultural games show a greater diversity of dynamical behaviors than their purely biological counterparts, including multiple fully polymorphic equilibria. Second, biocultural games on average exhibit greater equilibrium strategy diversity because of the countervailing influences of cultural transmission and natural selection. Therefore, knowledge of a strategy's influence on Darwinian fitness is not sufficient to infer the evolutionary consequences of biocultural games. Further, our results suggest that cultural transmission in the presence of natural selection may be an important mechanism maintaining behavioral diversity in natural populations.

Animals↗