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C S Kase

Publications and source records attributed to C S Kase.

80 records · Page 5Linked to original sources
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Stroke in south Alabama: incidence and diagnostic features--a population based study.

This study has attempted to identify all persons from an area of southern Alabama who had a stroke in 1980 and were hospitalized. Data were gathered on disease onset, clinical course, laboratory results, history of risk factors, and outcome. The age-adjusted incidence rates for initial stroke were 109 per 100,000 for whites and 208 per 100,000 for blacks. Age-specific rates were higher in blacks than whites, and highest for black females. The distribution of cases by type of stroke was: atherothrombotic (6%), embolic (26%), lacunar (13%), infarction of unspecified origin (40%), parenchymatous hemorrhage (8%), subarachnoid hemorrhage (6%), and unidentified type (1%). Blacks had higher incidence rates for hemorrhages, and black females had the highest incidence rate for lacunar stroke. The overall stroke incidence rates in this series were not significantly higher than those from prior population studies, suggesting that southern Alabama is not part of the so-called "Stroke Belt" area of the southeastern United States.

Adult↗
PubMedDate not supplied

The pilot Stroke Data Bank: definition, design, and data.

Four university centers collaborated to contribute 1158 patients with acute episodes of cerebrovascular disease to the pilot Stroke Data Bank, initiated by NINCDS in 1978. During the pilot project a standard set of data collection forms were developed and used at each of the collaborating centers. Data on clinical course, laboratory findings, therapy and outcome were gathered prospectively throughout the patient's hospitalization and at specified follow-up intervals. Using operational definitions of stroke sub-types, consecutive cases were systematically allocated to specific categories of brain and vascular pathology. The definitions were based on clinical criteria as well as on laboratory data, including computerized tomography (CT), and angiography findings. This paper describes the pilot Stroke Data Bank and presents the distribution of cases by diagnostic and demographic categories. It represents one of the largest series of prospectively collected stroke cases studied by CT (90% of the cases) and angiography (42%). Based upon the methods and processes of this pilot study, a main phase of the Stroke Data Bank has been established to address a number of questions pertaining to stroke classification, evolution, diagnosis, and prognosis.

Adult↗
PubMedDate not supplied

Somatosensory evoked potentials in pure sensory stroke and related conditions.

Somatosensory evoked potentials were reviewed for their correlation with CT scan and clinical features of ischemic "pure sensory stroke" and "pure sensorimotor stroke". Somatosensory evoked potentials were normal in all 11 cases of pure sensory stroke, and CT was normal in ten. The N2-P2 components of the somatosensory evoked potentials were abnormal in all 4 cases of pure sensorimotor stroke, and all had low density CT lesions in the lateral thalamus and/or posterior limb of the internal capsule. It is concluded that somatosensory evoked potentials and CT scans are routinely abnormal in pure sensorimotor stroke, but they are consistently normal in pure sensory stroke, and should not be interpreted as evidence against a clinical diagnosis of pure sensory stroke.

Adult↗
PubMedDate not supplied

[Antiaggregant treatment: present and future].

OBJECTIVE: To present current information on the use of antiaggregant agents and the possibilities of their further development. DEVELOPMENT: Aspirin is an established treatment for the prevention of cerebrovascular accidents (CVA) in patients with transitory ischemic attacks (TIA) or minor CVA. This agent reduces the risk by 20%. Ticlopidine has a slightly greater antiaggregant effect than Aspirin, but has the disadvantage of being more expensive and having serious haematological effects such as thrombotic thrombocytopenic purpura. In combination with Aspirin, ticlopidine is valuable in maintaining coronary stents permeable. Dipyridamole, used in combination with Aspirin reduces the risk of CVA by 37% which is more than either drug used alone. Clopidogrel, chemically related to ticlopidine, has a slightly greater protective effect without the serious haematological side-effects of the latter. Use of Aspirin in CVA, alone or combined with subcutaneous heparin, is effective in the early secondary prevention of CVAs. Future development of antiaggregant treatment includes various aspects, such as the use of Aspirin in primary and secondary prevention of CVA, its value in combination with other antiaggregant, antithrombotic and neuroprotector agents. CONCLUSIONS: Antiaggregant agents have meant a great advance in the treatment of CVA. In view of the relatively modest degree of protection given by Aspirin, future strategies will probably include combining it with other antiaggregant agents, antithrombotic drugs and neuroprotectors.

Acute Disease↗
PubMedDate not supplied

[Overestimation of the degree of stenosis in the intracranial internal carotid artery determined by magnetic resonance angiography compared to conventional arteriography].

INTRODUCTION: In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar comparison of the two techniques has been conducted in intracranial ICA. We report the case of a patient suffering from an acute ischemic stroke and symptomatic intracranial stenosis that was overestimated when MRA was used, compared to the results obtained using CA. CASE REPORT: We report the case of a 64-year-old male with a history of arterial hypertension, hypercholesterolemia and intermittent claudication who visited the emergency department because of the sudden onset of paresthesias in the left hemiface and hand. The cranial tomography scan performed in the emergency unit ruled out any acute bleeding or early signs of a stroke. Magnetic resonance (MR) diffusion imaging showed an acute ischemic stroke in the right parietal cortex. Extracranial MRA was normal and in the intracranial area a 73% stenosis was detected in the cavernous segment of the right ICA, whereas the use of CA showed the stenosis to be only 55%. On repeating the MRA to rule out a possible rechanneling of the ICA, the image obtained was exactly the same as the earlier one. CONCLUSIONS: Our observations suggest that, as occurs with the extracranial part, MRA tends to magnify the degree of stenosis in the intracranial vessels, and this technique would therefore appear to be less efficient than CA in the evaluation of intracranial stenoses.

Angiography↗