Biomedical subjects

C S May

Publications and source records attributed to C S May.

20 records · Page 2Linked to original sources

PubMed1975

The acute and chronic bronchodilator effects of ephedrine in asthmatic patients.

In eight asthmatic patients, there was no change in the bronchodilator response to a single dose of ephedrine (22 mg) given alone or in a compound tablet, after treatment with ephedrine (11 mg three times a day) or one tablet three times a day for 2 weeks. 2 There was no deterioration in lung function during the 2 week treatment period with either ephedrine or the compound tablet. 3 An inter-patient variation was noted in the plasma ephedrine concentraition required for bronchodilatation. 4 The half-life of theophylline did not change after chronic treatment with the tablets, one three times a day for 2 weeks.

Administration, Oral↗

PubMed1975

Measurement of plasma prednisolone in man.

1. A modification of the competitive protein binding assay for prednisolone described by English, Chakraborty & Marks (1974) is presented. 2. Addition of pg quantities of [3H]-prednisolone following oral dosage with prednisone or prednisolone. 3. Mean plasma half-life and peak plasma concentrations in patients with respiratory disease seen following prednisolone administration agree well with previous studies in healthy volunteers performed by other workers using competitive protein binding and radioimmunoassay techniques. 4. A considerable inter-patient variation in bioavailability after a standard dose of prednisolone (20 mg) was noted.

Administration, Oral↗