PubMed Health⌕ Search

Biomedical subjects

C S Quintana

Publications and source records attributed to C S Quintana.

7 recordsLinked to original sources

The outcome of cardiac operations in infants weighing two kilograms or less.

OBJECTIVE: A review of our recent experience of operating on infants weighing 2 kg or less who had congenital heart disease was performed to determine the outcome of early surgical repair or palliation. METHODS: A retrospective review of hospital records was performed for infants who weighed 2 kg or less and who were identified to have undergone cardiac operation at our institution January 1992 to June 1997. The data collected included age, weight, gestational age, cardiac diagnosis, surgical procedure, and outcome measures such as length of stay, morbidity, and mortality rate. Outpatient charts were reviewed for follow-up survival and cardiac status. RESULTS: Thirty-three operations were performed on 30 patients. Median age at operation was 19.5 days (1 to 140 days), and median weight was 1.8 kg (1.1 to 2.0 kg). Cardiac diagnoses varied, with coarctation of the aorta and tetralogy of Fallot most common. Twenty-four patients were born at 37 or fewer weeks' gestation. Hospital survival was 83% with no difference in mortality rates based on age, weight, or type of surgical procedure. Premature infants tended to have worse hospital survival. Median postoperative length of stay was 39 days (6 to 122 days). Median duration of mechanical ventilation in survivors was 6 days (2 to 24 days). Neurologic complications were documented in eight patients. Of the 25 hospital survivors, 20 (80%) are alive with good cardiac status at a mean follow-up of 13 months. CONCLUSION: Cardiac operations in a selected group of infants weighing 2 kg or less can provide acceptable hospital survival. In most instances, complete repair is possible with good medium-term outcome in the survivors. Investigation into neurologic outcomes in these patients is warranted.

Cardiac Surgical Procedures↗

Significance of distal false lumen after type A dissection repair.

Fifty-eight patients underwent repair of acute type A dissection between 1986 and 1992. Follow-up aortogram, computed tomographic scan with contrast, magnetic resonance imaging scan, or a combination of these tests was available in 38 patients with preoperatively patent distal false lumens. All distal anastomoses were constructed with the open technique during a period of circulatory arrest. There were 25 suture and 13 intraluminal graft anastomoses. Patency of the distal false lumen was found in 47.3%. Use of the intraluminal graft for the distal anastomosis decreased patency, although not significantly (4/13, 30% versus 14/25, 56%; p = 0.14). The direction of flow into the false lumen was antegrade in 11 of 24 (45.8%) of sutured anastomoses and 0 of 9 intraluminal graft anastomoses (p < 0.01). Actuarial survival at 5 years for patients with closed distal false lumen was 95% +/- 4.8% versus 76% +/- 15% for patients with patency of the distal false lumen (p = not significant). Event-free survival at 5 years for both groups was 84% +/- 8.3% (closed false lumen) and 63% +/- 13.5% (patency of distal false lumen; p = not significant). This experience indicates that in the treatment of acute type A dissections, operative strategy and anastomotic technique play a role in reducing the incidence of patency and related complications of the distal false lumen.

Actuarial Analysis↗

Aortic sarcoma four years after Dacron graft insertion.

Malignant fibrous histiocytoma of the aorta developed in a 70-year-old man 4 years after he had undergone repair of a type B aortic dissection with Dacron graft interposition. The tumor surrounded the graft externally and involved the adventitia of the aorta near the proximal anastomosis. Clinically and radiologically it mimicked a pseudoaneurysm of the descending thoracic aorta. Primary aortic sarcomas are extremely uncommon and only rarely reported in association with prior aortic graft insertion.

Aged↗

Coronary bypass with ejection fraction of 0.20 or less using centigrade cardioplegia: long-term follow-up.

Forty-two patients with an ejection fraction of 0.20 or less underwent coronary artery bypass grafting from 1986 to 1990 using a method of myocardial protection we term "centigrade cardioplegia," combining single-dose, cold, crystalloid cardioplegia, systemic hypothermia, and local hypothermia. Thirty-day mortality was 4.8% (2/42). Perioperative morbidity included two myocardial infarctions (4.8%) and one stroke (2.4%), which fully resolved. Postoperative left ventricular function improved (left ventricular ejection fraction, 0.157 +/- 0.028 to 0.226 +/- 0.085; p < 0.0002), as did New York Heart Association class (3.4 +/- 0.73 to 1.8 +/- 0.63; p < 0.0001) and Canadian class (3.3 +/- 0.81 to 0.61 +/- 0.92). Survival, 88% at 1 year, declined to 68% at 3 years and 34% at 6 years. This high-risk group had very acceptable short-term results, indicating adequate intraoperative myocardial protection. Four clinical variables were associated with long-term survival: (1) chief complaint of pain only (p = 0.05), (2) history of unstable angina (p = 0.04), (3) Canadian class less than IV (p = 0.05), and (4) New York Heart Association class less than IV (p = 0.05). Reduced survival, although not statistically significant (p = 0.07), was noted for right ventricular ejection fraction of 0.30 or less. These factors may help predict which patients with severe left ventricular dysfunction will benefit from revascularization.

Angina Pectoris↗

Localization of parathyroid lesions: blind study for surgeons.

Success in the treatment of primary hyperparathyroidism rest in the accurate localization and removal of the diseased gland or glands. Computerized tomography and nuclear imaging scans are being used to localize abnormal parathyroid tissue. In the present study, fifteen consecutive patients undergoing surgery for primary hyperparathyroidism were all subjected to these ancillary studies. Results were not revealed to the operating team. In all instances an adenoma was localized during neck exploration. CT Scan failed to localize 73% of the affected glands. Nuclear scans missed almost fifty percent of the parathyroid adenomas. The low yield of these ancillary localizing tests makes them unnecessary in the routine evaluation of patients undergoing surgery for primary hyperparathyroidism.

Adenoma↗