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Biomedical subjects

C S Samorodin

Publications and source records attributed to C S Samorodin.

7 recordsLinked to original sources

Ketoconazole-treated sporotrichosis in a veterinarian.

A 63-year-old veterinarian acquired sporotrichosis presumably from handling an infected cat. Treatment was successfully completed with ketoconazole, 200 to 400 mg a day for eight weeks. No side effects were noted.

Animals↗

Bilateral inflammatory carcinoma of the male breast.

A case of bilateral inflammatory carcinoma of the breast in a man is described. The superficial dermal lymphatics were invaded by the malignancy producing edema and vascular congestion of the upper dermis. This hyperemia produces the clinical appearance of an inflammatory reaction.

Aged↗

Thiabendazole-induced toxic epidermal necrolysis.

Toxic epidermal necrolysis (TEN) is a syndrome that may develop from a number of different stimuli, including drug administration, staphylococcal infection, vaccine administration, and blood dyscrasias. A 29-year-old woman developed TEN from the systemic administration of thiabendazole. Although various cutandous adverse reactions have been attributed to the administration of this medication, this is the first case to indicate that orally administered thiabendazole may also produce TEN. Although acutely ill at the time of hospitalization, the patient showed a prompt response to treatment with prednisone.

Adult↗

Cutaneous protothecosis in a patient receiving immunosuppressive therapy.

A 30-year-old recipient of a renal transplant, who was receiving immunosuppressive therapy, developed cutaneous abscesses from which an organism of the genus Prototheca was cultured. The patient died of Klebsiella septicemia. At the time of death, pure cultures of Prototheca and Candida organisms were grown from separate skin lesions. Prototheca is a genus of achloric algae. Cultural, microscopical, and staining characteristics separate these organisms from the yeast and fungi. Cutaneous protothecosis was first described in 1964 by Davies et al in an otherwise healthy African rice farmer. Since that time, nine other cases have been reported. However, only a single case has been described in a patient receiving immunosuppressive drugs, a woman with carcinoma of the breast who was receiving chemotherapy with multiple agents.

Abscess↗