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C Sabelli

Publications and source records attributed to C Sabelli.

10 recordsLinked to original sources
PubMed1987

Ultrasonography and echo-guided fine-needle biopsy in the diagnosis of focal fatty liver change.

The usefulness of ultrasound and echo-guided fine-needle biopsy (FNB) in the diagnosis of focal fatty liver change (FFLC) is stressed, on the basis of a retrospective series of 21 patients (8 of whom with a past history of primary cancer), followed-up for a mean period of 13.7 months. FFLC presented with various echographic patterns, shapes, dimensions and localizations. In 17 patients the diagnosis of FFLC was made by FNB, yielding cytologic and/or histological samples with steatotic, but also normal, hepatocytes. In another 4 patients the diagnosis was made by echographic follow-up. In all patients, clinical, hematological and echographic follow-up excluded the onset of neoplastic disease, confirming the high specificity of FNB in diagnosing FFLC. The possibility of changing appearance over time, and the inconstant correlation of FFLC with known causes of hepatic steatosis are discussed, as well as the hypothesis that the focal defect seen with ultrasound, could be an area of normal hepatic tissue in a fatty liver. The authors affirm the necessity to perform FNB on each doubtful lesion, but certainly when the patient has a history of malignancy.

Adult↗
PubMed1986

Ultrasound-guided fine-needle aspiration biopsy in the diagnosis of hepatic hemangioma.

Fine-needle biopsy of hepatic hemangioma is discussed on the basis of a series of 10 biopsies performed on eight patients. The fine needle biopsies were executed because of the atypical sonographic pattern of some lesions, or in order to exclude malignancy for others (five patients were known to have neoplasms). No complication presented during or after the punctures. In six cases cytologic samples included capillary vessels or endothelial cells, supplying the diagnosis of hemangioma. It is concluded that fine-needle biopsy of a hepatic hemangioma is not loaded with complications, and moreover can yield true positive information in 60% of cases.

Aged↗
PubMed1983

Impaired clearance of cholephilic anions in Rotor syndrome.

The behaviour of some cholephilic anions has been studied in three male patients (two of whom are brothers) affected with Rotor syndrome. The unconjugated bilirubin clearance was markedly reduced with impairment of the plasma-liver transfer constant rate (uptake defect). BSP retention at 45 min. was elevated without late rise of the anion. Transport maximum ("Tm") of BSP was slightly reduced; relative hepatic storage capacity of BSP ("S") was significantly impaired. Plasmatic retention of 131-I-Rose Bengal was increased with a diminished hepatic uptake of the compound. The hepatic excretion of IDA-derivatives was impaired, but less for parabutyl-IDA than for diethyl-IDA. It is concluded that in Rotor syndrome there exists an alteration of uptake and storage of several cholephilic organic anions: the alteration is common not only to substances that undergo intracellular conjugation--such as bilirubin and BSP--but also to substances that are not metabolized--such as Rose Bengal and IDA--derivatives. Finally the authors suggest that the Rotor syndrome and so--called "Hepatic storage disease" are the same condition.

Adult↗
PubMedDate not supplied

[Adherence test in relation to caries activity].

The amount of streptococcus mutans in saliva has been suggested as a way of estimating caries activity (Klock; Krasse, 1979; Newbrum et al 1984; Sabelli, 1985; Thylstrop; Fejerskov, 1988). This study was carried out no evaluate the relationship between an adherence test (formation of streptococcus mutans colonies which allows to group individuals according to level of risk) with the caries activity was determine in 137 children and samples of saliva (0.1 ml) were obtained from each of them. They were processed in mitis salivarius sucrose al 37 degrees C. during 48 hours. According to the reaching each child caries activity was recorded as percentage of non-active caries in the mean values in each group were statistically analyzed using Kramer's extension of Duncan's test. Significant differences were found only between high and low level risk groups. In the care of extreme groups the test seems to be valuable form estimation of caries activity.

Adolescent↗