[Foreign body aspiration].
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Biomedical subjects
Publications and source records attributed to C Schöttes.
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Nineteen workers (18 males, 1 female) of a garbage dump (mean age 39.9 years, range 19-58 years) were admitted to our hospital because of inhalation of a hydrazine-like gas of unknown origin. They complained of an ammoniacal odor with sweet taste followed by burning of the eyes, rawness in the throat and dyspnea, dizziness and nausea. Ten patients (group A) arrived about 2 h after they had experienced their first symptoms. The nine other patients (group B) were admitted about 70 h later. On the second day the white cell counts were significantly elevated compared to those of the days before and after (P < 0.02-0.005). The lung function showed in two patients a moderate obstruction. The PO2 was significantly reduced within 1 to 12 h after admission (P < 0.02-0.005) compared to the measurement before (P < 0.005) and after 25 (P < 0.02) and 50 (P < 0.01) h. A significantly reduced PCO2 was found after 25 h compared to the time of admission (P < 0.03). These investigations show that workers of a garbage dump had an alarming decrease of oxygen after inhalation of nitrogenous gases released by the trash.
A total of 120 samples of serum were obtained from 8 patients with COPD and submitted to a comparative analysis of serum theophylline levels employing the TDX and the EMIT methods of determination. At the same time, two different slow-release preparations of theophylline were compared, their kinetics investigated, and their effects tested using body plethysmography. For this open, randomized cross-over preliminary investigation, numerous inclusion and exclusion criteria were applied.
On the basis of the five-year study (1984-1988) presented herein, we have been able to demonstrate that, under conditions of smog, an increase in respiratory diseases can occur. Our results also show that cardiovascular diseases decrease simultaneously, an observation that has not so far been reported in the literature. A possible reason for this observation is, perhaps, an information effect, or an influence effect induced by warnings given in the media about the negative health-related consequences for those who leave their homes, in particular those consequences applicable to patients with cardiovascular disorders. The pathological process is traceable to a multifactorial occurrence, the temperature of the air having a decisive influence. To date, the influence of indoor pollution has not yet been clarified.