Biomedical subjects

C Schaap

Publications and source records attributed to C Schaap.

9 recordsLinked to original sources

PubMed1992

McKusick-Kaufman syndrome: the diagnostic challenge of abdominal distension in the neonatal period.

We report a newborn girl with McKusick-Kaufman syndrome who presented at birth with severe life-threatening abdominal distension due to hydrometrocolpos. In children with polydactyly and cystic masses in the lower abdomen should hydrometrocolpos be especially considered. Ultrasonography is of great value in the correct assignment of lower abdominal tumours, but should be completed by vagino(cysto)scopy when hydrometrocolpos is suspected.

Abnormalities, Multiple↗

PubMed1992

Do drop-outs differ from successfully treated obsessive-compulsives?

The most common reasons given by patients for dropping out of treatment are: environmental constraints, dissatisfaction with services and that they no longer need help. In this study two groups of patients suffering from obsessive-compulsive disorders are compared. The drop-outs' reasons for terminating treatment are compared with the comments of patients who completed the therapy successfully. Drop-outs differ from successfully treated OCD's in five respects: they appear to be less obsessive-compulsive; they have more discongruent treatment expectations; they are more critical of the therapist; they experience less anxiety in carrying out homework assignments; they less frequently come under pressure from people close to them.

Adaptation, Psychological↗

PubMed1992

Opitz-C syndrome: on the nosology of mental retardation and trigonocephaly.

We report on two patients with a complicated form of trigonocephaly. The first patient has the Opitz-"C"-trigonocephaly syndrome. The second patient had initially a delayed motor development, but finally attained normal intelligence. A review of 22 patients with Opitz-C syndrome from the literature is presented. Most of the typical facial dysmorphism can be regarded as part of a trigonocephaly "sequence" rather than presenting characteristic features of a syndrome. More specific are the intra-oral anomalies, abnormally modelled ears, cardiac anomalies and neonatal hypotonia. All surviving patients are severely retarded. Since almost all patients are sporadic cases we suggest that the "C"-syndrome is a cytogenetically yet undetectable microdeletion syndrome.

Abnormalities, Multiple↗

PubMed1991

The effects of a somatostatin analogue on the metabolism of an infant with Beckwith-Wiedemann syndrome and hyperinsulinaemic hypoglycaemia.

Hypoglycaemia is a frequent finding during the neonatal period and may be due to insulin overproduction. Patients with Beckwith-Wiedemann syndrome have reduced numbers of somatostatin-producing cells and decreased extractable somatostatin. In this study the effect of long-acting somatostatin (SMS201-995) on the glucose and insulin levels in an infant with Beckwith-Wiedemann syndrome and hyperinsulinaemic non-ketotic hypoglycaemia is described. SMS201-995 lowered basal insulin levels while maintaining normal glucose and insulin homeostasis. During fasting however, both glucose levels declined rapidly whereas insulin levels did not. The absence of both ketosis and elevated levels of free fatty acids and lactate during hypoglycaemia, as observed in our patient, are important diagnostic clues since the insulin levels themselves may sometimes be only slightly elevated.

Beckwith-Wiedemann Syndrome↗

PubMed1991

Verbal analysis of doctor-patient communication.

A microscopic analysis of doctor-patient communication in the general practitioner's surgery is presented. Verbatim transcripts of 85 medical interviews, audiotaped in a natural situation were analysed. The effects of type of complaint, patient gender and physician gender on the process of verbal communication were assessed. This study focused upon the relational aspects of communication, using Stiles' Verbal Response Mode coding system (VRM), and, to a limited extent, upon the content of patient's complaints--whether they were primarily somatic or of a psychosocial nature. The hypothesis of an asymmetrical relation between physician and patient was confirmed. Results partially confirmed the hypothesis that interviews of psychosocial patients take more time than those of somatic patients. There was also some evidence that psychosocial patients try to exert more control over the conversation as compared to somatic patients. Male and female patients differed in the way they elaborated their complaints. When telling their complaints, women referred more to persons (family, friends, colleagues) than did men. In case of male GP's, the interviews of female patients took more time than those of male patients. The largest differences were between male and female physicians. In agreement with the hypothesis males were more imposing and presumptuous (giving more advisements and interpretations). Female GP's were more attentive and non-directive (giving more subjective and objective information and acknowledgements). The medical interviews of female GP's took more time than the interviews of their male colleagues. The results are discussed in the light of theoretical concepts of harmony and discrepancy with respect to doctor-patient communication and theories about gender differences.

Adolescent↗

PubMed1989

[Dosage aerosols; problems with the inhalation technic].

The inhalation techniques of 77 patients using a dosing aerosol were videotaped before, immediately after and (in 55 cases) three weeks after they viewed an instruction video tape. The inhalation technique was assessed on 9 points. Before the instruction only 2% had a correct and 49% a completely faulty technique. After instruction, these figures were 65% and 13%, respectively. After three weeks, 12% were found to have regressed to only partially correct use.

Administration, Inhalation↗

PubMed1989

The significance of the patient-therapist relationship in the treatment of obsessive-compulsive neurosis.

Results are presented of two studies into the predictive value of the therapeutic relationship in the treatment of 60 and 25 obsessive-compulsive patients. A relationship was found between the therapist's score on the Barret-Lennard Relationship Inventory, assessed after the second and 10th sessions. As far as the patients' scores were concerned, however, a significant correlation with outcome was found only after the 10th session.

Follow-Up Studies↗

PubMed1987

Exposure and response prevention in patients with obsessions.

The outpatient treatment of patients with obsessions alone is often said to be less successful compared to the outpatient treatment of patients with both obsessions and compulsive symptoms. This article presents the outcome of the treatment of 26 obsessive patients. The success rate, measured after 10 treatment sessions, was 73%. At follow-up after 12-36 months, improvement appeared to have been maintained or to have increased in 61.5% of the patients, figures comparable to the outcome of patients with both obsessions and compulsions.

Adolescent↗

PubMed1985

Hydrogen breath test in schoolchildren.

The frequency of negative hydrogen breath tests due to colonic bacterial flora which are unable to produce hydrogen was determined after oral lactulose challenge in 98 healthy Dutch schoolchildren. There was a negative result in 9.2%. The probability of a false normal lactose breath test (1:77) was calculated from these results together with those from a separate group of children with lactose malabsorption (also determined by hydrogen breath test). A study of siblings and mothers of subjects with a negative breath test did not show familial clustering of this condition. Faecal incubation tests with various sugars showed an increase in breath hydrogen greater than 100 parts per million in those with a positive breath test while subjects with a negative breath test also had a negative faecal incubation test. The frequency of a false negative hydrogen breath test was higher than previously reported, but this does not affect the superiority of this method of testing over the conventional blood glucose determination.

Adolescent↗